ArticleCritical care medicine2015
Morbidity and survival probability in burn patients in modern burn care.
Article in Critical care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
96 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence and Mortality of Acute Respiratory Distress Syndrome in Patients With Burns: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2021Pooled it
- Impact of Real-Time Therapeutic Drug Monitoring on the Prescription of Antibiotics in Burn Patients Requiring Admission to the Intensive Care Unit.Antimicrobial agents and chemotherapy · 2018Trial
- Inhaled AP301 for treatment of pulmonary edema in mechanically ventilated patients with acute respiratory distress syndrome: a phase IIa randomized placebo-controlled trial.Critical care (London, England) · 2017Trial
- Flurbiprofen Axetil Enhances Analgesic Effects of Sufentanil and Attenuates Postoperative Emergence Agitation and Systemic Proinflammation in Patients Undergoing Tangential Excision Surgery.Mediators of inflammation · 2015Trial
- TMAO Correlates with Transcriptomic Signatures of Leukocyte Activation and Systemic Inflammation Following Burn Injury.Journal of burn care & research : official publication of the American Burn Association · 2026Article
- Preoperative Glucose-Albumin Ratio and Its Association with Postoperative Outcomes in Critically Ill Adult Burn Patients: A Retrospective Cohort Study of 1119 Patients.Diagnostics (Basel, Switzerland) · 2026Article
- Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Serious Infections in Burn-Injured Adults: A Retrospective Single-Center Study from 1997 to 2023.Journal of burn care & research : official publication of the American Burn Association · 2026Article
- The tale of two states: mortality outcomes and burn severity among in-state versus out-of-state burn victims treated in the Texas Panhandle.Proceedings (Baylor University. Medical Center) · 2026Article
- Outcomes of Burn Patients Admitted Initially to a Non-Burn Center Intensive Care Unit in Romania: A Retrospective Exploratory Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Burn Selection: How Fire Injury Shaped Human Evolution.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026Review
- The role of artificial intelligence in burn assessment, complication diagnosis, and outcome prediction: a narrative review.Burns & trauma · 2026Review
- Expanding the Limits of Burn Care: Survival After a 92% Total Body Surface Area Burn.European burn journal · 2025Article
- Chronic Malnutrition Increases the Risk of Nosocomial Infections in Pediatric Burn Patients: A Retrospective Cohort from the National Institute of Child Health.Annals of burns and fire disasters · 2025Article
- Article
- Review of the 100 Most Cited Articles inEuropean burn journal · 2025Review
- From Data to Decisions: Leveraging Retrieval-Augmented Generation to Balance Citation Bias in Burn Management Literature.European burn journal · 2025Article
- Prehospital and emergency data analysis in burn patients: Mortality predictors and response times over five years.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- Country economic status is strongly associated with burn survival - validation of the (modified) ABSI.International journal for equity in health · 2025Article
- Health Care Resource Use and Costs After Hospitalization With Multiple Organ Dysfunction in Children.JAMA network open · 2025Article
- CD42-Enriched Extracellular Vesicles Contribute to Increased Platelet Aggregation and Possibly Organ Damage in Patients with Burn Injury Complicated by Sepsis.International journal of nanomedicine · 2025Article
36 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
objectiveCharacterizing burn sizes that are associated with an increased risk of mortality and morbidity is critical because it would allow identifying patients who might derive the greatest benefit from individualized, experimental, or innovative therapies. Although scores have been established to predict mortality, few data addressing other outcomes exist. The objective of this study was to determine burn sizes that are associated with increased mortality and morbidity after burn. DESIGN AND PATIENTS: Burn patients were prospectively enrolled as part of the multicenter prospective cohort study, Inflammation and the Host Response to Injury Glue Grant, with the following inclusion criteria: 0-99 years old, admission within 96 hours after injury, and more than 20% total body surface area burns requiring at least one surgical intervention.
settingSix major burn centers in North America. MEASUREMENTS AND MAIN
resultsBurn size cutoff values were determined for mortality, burn wound infection (at least two infections), sepsis (as defined by American Burn Association sepsis criteria), pneumonia, acute respiratory distress syndrome, and multiple organ failure (Denver 2 score>3) for both children (<16 yr) and adults (16-65 yr). Five hundred seventy-three patients were enrolled, of which 226 patients were children. Twenty-three patients were older than 65 years and were excluded from the cutoff analysis. In children, the cutoff burn size for mortality, sepsis, infection, and multiple organ failure was approximately 60% total body surface area burned. In adults, the cutoff for these outcomes was lower, at approximately 40% total body surface area burned.
conclusionsIn the modern burn care setting, adults with over 40% total body surface area burned and children with over 60% total body surface area burned are at high risk for morbidity and mortality, even in highly specialized centers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.