Evidence map›Paper›PMID 25559153›Full record

ReviewPhysiology (Bethesda, Md.)2015

Sex-based differences in skeletal muscle kinetics and fiber-type composition.

K M Haizlip, B C Harrison, L A Leinwand

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Physiology (Bethesda, Md.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 280 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
280citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

280 citing papers in PubMed, 12 syntheses or guidelines pooled it.

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220 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

K M HaizlipDepartment of Molecular, Cellular, and Developmental Biology, BioFrontiers Institute, University of Colorado at Boulder, Boulder, Colorado.
B C HarrisonDepartment of Molecular, Cellular, and Developmental Biology, BioFrontiers Institute, University of Colorado at Boulder, Boulder, Colorado.
L A LeinwandDepartment of Molecular, Cellular, and Developmental Biology, BioFrontiers Institute, University of Colorado at Boulder, Boulder, Colorado leslie.leinwand@colorado.edu.

Funding

MYOSIN GENE DIVERSITY AND FUNCTIONR01GM029090 · NIGMS · YESHIVA UNIVERSITY · PI Leslie Anne Leinwand · 1985 to 2026
$12.3M
POSTGRADUATE TRAINING IN CARDIOVASCULAR RESEARCHT32HL007822 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI BUTTRICK, PETER N., LEINWAND, LESLIE ANNE · 1996 to 2023
$6.2M
MicroRNAs, Muscle Injury, Adaptation, and AgingK01AR055676 · NIAMS · UNIVERSITY OF COLORADO · PI HARRISON, BROOKE · 2010 to 2014
$619k
NHLBI NIH HHS T32 HL007822NIAMS NIH HHS 5K01 AR-55676NIAMS NIH HHS K01 AR055676NIGMS NIH HHS GM-029090-30A1S1NIGMS NIH HHS GM-29090-31NIGMS NIH HHS R01 GM029090
6 · The paper itself

Abstract

Previous studies have identified over 3,000 genes that are differentially expressed in male and female skeletal muscle. Here, we review the sex-based differences in skeletal muscle fiber composition, myosin heavy chain expression, contractile function, and the regulation of these physiological differences by thyroid hormone, estrogen, and testosterone. The findings presented lay the basis for the continued work needed to fully understand the skeletal muscle differences between males and females.

Indexed as

Sex CharacteristicsAnimalsFemaleHumansKineticsMaleMuscle ContractionMuscle Fibers, SkeletalMyosin Heavy ChainsThyroid HormonesMyosin Heavy ChainsThyroid Hormones

Identifiers

PMID25559153
PMCPMC4285578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.