Trial reportNutrients2014
Heart rate variability and cognitive function following a multi-vitamin and mineral supplementation with added guarana (Paullinia cupana).
Trial report in Nutrients, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comment on Hack et al. Effect of Guarana (Nutrients · 2023Pooled it
- Effect of Guarana (Nutrients · 2023Pooled it
- Effects of Acute Guarana (Nutrients · 2024Trial
- Cognitive effects of guarana supplementation with maximal intensity cycling.The British journal of nutrition · 2023Trial
- Trial
- Trial
- Cognitive Performance Enhancement Induced by Caffeine, Carbohydrate and Guarana Mouth Rinsing during Submaximal Exercise.Nutrients · 2017Trial
- Acute Effects of Guarana (Sports (Basel, Switzerland) · 2026Article
- Multivitamins and cognitive health in older adults: bridging evidence, gaps, and controversies - a comprehensive narrative review.Annals of medicine and surgery (2012) · 2026Review
- Revealing the Acute Effects of Dietary Components on Mood and Cognition: The Role of Autonomic Nervous System Responses.Brain sciences · 2023Review
- Gender Differences in the Frequency of Positive and Negative Effects after Acute Caffeine Consumption.Nutrients · 2023Article
- Mental Performance and Sport: Caffeine and Co-consumed Bioactive Ingredients.Sports medicine (Auckland, N.Z.) · 2022Review
- Fungal Endophytic Community Associated with Guarana (Journal of fungi (Basel, Switzerland) · 2020Article
- Phytochemicals for Improving Aspects of Cognitive Function and Psychological State Potentially Relevant to Sports Performance.Sports medicine (Auckland, N.Z.) · 2019Review
- Review
- Heart-rate variability: a biomarker to study the influence of nutrition on physiological and psychological health?Behavioural pharmacology · 2018Review
- Xanthine-Catechin Mixture Enhances Lithium-Induced Anti-Inflammatory Response in Activated MacrophagesBioMed research international · 2017Article
- Effect of Carbohydrate Intake on Maximal Power Output and Cognitive Performances.Sports (Basel, Switzerland) · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to assess cognitive performance and heart rate variability (HRV) following the ingestion of either a multi-vitamin-mineral preparation supplemented with 300 mg guarana (Ac); a caffeine supplement (C) or a placebo supplement (Pl). Fifty-six subjects took part in a randomized, double-blind crossover design, consisting of three experimental sessions ran on a different day. Cognitive performance was assessed using a go/no-go task and a simple reaction time (SRT) task. HRV was assessed in the time domain (RMSSD) and in the frequency domain (HF) and cognitive tasks were performed before ingestion, 15 min after ingestion and then every 15 min over the course of 3 h. Responses were faster (without change in accuracy) when the go/no-go task was performed between 30 and 90 min after ingestion of Ac (4.6% ± 0.8%, p < 0.05). No effect was observed on SRT task. A significant decrease in HRV was observed during the first hour under C and Pl, whereas HRV remained stable under Ac. The results suggest that the ingestion of a multi-vitamin-mineral with added guarana improves decision-making performance and is accompanied by a stable autonomic nervous system regulation during the first hour.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.