Evidence map›Paper›PMID 25558471›Full record

ArticleMolecular & cellular oncology2014

Cell survival is dicey without Dicer.

Clare M Adams, Christine M Eischen

Open access · hybridAbstract read
In one paragraph

Article in Molecular & cellular oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Clare M AdamsDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN.
Christine M EischenDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN.
Nashville Oncology Associates · US

Funding

Regulation of Myc-Mediated TumorigenesisR01CA148950 · NCI · VANDERBILT UNIVERSITY · PI EISCHEN, CHRISTINE M. · 2011 to 2015
$1.7M
Novel Mechanism for Myc-Induced ApoptosisF31CA165728 · NCI · VANDERBILT UNIVERSITY · PI ADAMS, CLARE MARIE · 2012 to 2014
$80k
NCI NIH HHS F31 CA165728NCI NIH HHS R01 CA148950
6 · The paper itself

Abstract

The cellular requirements of Dicer, an essential miRNA processing enzyme, and the consequences of altered levels of it on tumorigenesis are incompletely understood. We review the effects of Dicer loss in cells of different origin and whether loss of p53 permits cell survival and growth in the absence of Dicer.

Indexed as

Dicerlymphomap53tumorigenesis

Identifiers

PMID25558471
PMCPMC4279215
OpenAlexW2080647058

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.