Evidence map›Paper›PMID 25558464›Full record

ArticleNeurophotonics2014

Fast calcium sensor proteins for monitoring neural activity.

Aleksandra Badura, Xiaonan Richard Sun, Andrea Giovannucci, Laura A Lynch, Samuel S-H Wang

Abstract read
In one paragraph

Article in Neurophotonics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed.

  1. Article
  2. Precise calcium-to-spike inference using biophysical generative models.bioRxiv : the preprint server for biology · 2026
    Article
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aleksandra BaduraPrinceton University, Princeton Neuroscience Institute and Department of Molecular Biology, Princeton, New Jersey 08544, United States.
Xiaonan Richard SunPrinceton University, Princeton Neuroscience Institute and Department of Molecular Biology, Princeton, New Jersey 08544, United States.
Andrea GiovannucciPrinceton University, Princeton Neuroscience Institute and Department of Molecular Biology, Princeton, New Jersey 08544, United States.
Laura A LynchPrinceton University, Princeton Neuroscience Institute and Department of Molecular Biology, Princeton, New Jersey 08544, United States.
Samuel S-H WangPrinceton University, Princeton Neuroscience Institute and Department of Molecular Biology, Princeton, New Jersey 08544, United States.

Funding

Imaging adaptive cerebellar processing at cellular resolution in awake miceR01NS045193 · NINDS · PRINCETON UNIVERSITY · PI WANG, SAMUEL SHENG-HUNG · 2003 to 2024
$7.5M
Viral Brainbow: tracing brain circuits with connection order specificityRC1NS068414 · NINDS · PRINCETON UNIVERSITY · PI CARD, JOHN PATRICK, ENQUIST, LYNN W. · 2009 to 2010
$993k
Transcending dynamic and kinetic limits for neuronal calcium sensingR21NS092320 · NINDS · PRINCETON UNIVERSITY · PI WANG, SAMUEL SHENG-HUNG · 2015 to 2016
$446k
NINDS NIH HHS R01 NS045193NINDS NIH HHS R21 NS092320NINDS NIH HHS RC1 NS068414
6 · The paper itself

Abstract

A major goal of the BRAIN Initiative is the development of technologies to monitor neuronal network activity during active information processing. Toward this goal, genetically encoded calcium indicator proteins have become widely used for reporting activity in preparations ranging from invertebrates to awake mammals. However, slow response times, the narrow sensitivity range of Ca

Indexed as

calcium indicator proteinsGCaMPin vivo imagingkinetics

Identifiers

PMID25558464
PMCPMC4280659

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.