Evidence map›Paper›PMID 25558382›Full record

ArticleIranian Red Crescent medical journal2014

Comparing the Healing Effects of Arnebia euchroma Ointment With Petrolatum on the Ulcers Caused by Fractional CO2 Laser: A Single-Blinded Clinical Trial.

Jale Aliasl, Fariba Khoshzaban, Behrooz Barikbin, Mohsen Naseri, Mohammad Kamalinejad, Fatemeh Emadi, Zahra Razzaghi, Daryush Talei, Maryam Yousefi, Fatemeh Aliasl and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Iranian Red Crescent medical journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
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  3. A randomised control trial to compareJournal of research in nursing : JRN · 2025
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  6. Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2016
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Jale AliaslTraditional Medicine Clinical Trial Research Center, Shahed University, Tehran, IR Iran.
Fariba KhoshzabanTraditional Medicine Clinical Trial Research Center, Shahed University, Tehran, IR Iran.
Behrooz BarikbinLaser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
Mohsen NaseriTraditional Medicine Clinical Trial Research Center, Shahed University, Tehran, IR Iran.
Mohammad KamalinejadDepartment of Pharmacognosy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
Fatemeh EmadiTraditional Medicine Clinical Trial Research Center, Shahed University, Tehran, IR Iran.
Zahra RazzaghiLaser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
Daryush TaleiMedicinal Plant Research Center, Shahed University, Tehran, IR Iran.
Maryam YousefiSkin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
Fatemeh AliaslDepartment of Traditional Pharmacy, Faculty of Traditional Medicine, Tehran University of Medical Sciences, Tehran, IR Iran.
Maryam BaratiLaser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
Parvaneh Mohseni-MoghaddamTraditional Medicine Clinical Trial Research Center, Shahed University, Tehran, IR Iran.
Seyed Abbas HasheminejadTraditional Medicine Clinical Trial Research Center, Shahed University, Tehran, IR Iran.
Hossein Esmailzad NamiTraditional Medicine Clinical Trial Research Center, Shahed University, Tehran, IR Iran.
Shahed University · IRShahid Beheshti University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArnebia euchroma ointment (AEO) has been used in Iranian traditional medicine for burn wound healing.

objectivesThe aim of this study is to evaluate wound healing efficacy of AEO in burn wounds after fractional Co2 laser. PATIENTS AND

methodsThis split-face, single-blinded, single-center clinical study was performed in Shohada-e-Tajrish Hospital, Tehran, Iran. A total of 26 subjects with facial acne scar, who were to receive fractional CO2 laser resurfacing were recruited. After laser procedure, AEO was applied to one side of the face and petrolatum on the other side for wound healing. Digital photographs were taken from acne scar area before resurfacing and on each of the assessment sessions. Three researchers, who were unaware of the applied medications, assessed these digital photographs for erythema, edema, epithelial confluence, crusting/scabbing, and general wound appearance. Subject's irritations such as dryness and itching were evaluated on the second, fifth, and seventh days.

resultsOur study indicated higher epithelial confluence and general wound appearance scores (P = 0.045 for both) and less erythema and edema on fifth day in petrolatum (P = 0.009 and P = 0.034, respectively). The results showed less crusting and erythema (P = 0.016 and P = 0.035, respectively) and higher general wound appearance scores in petrolatum on the second day (P = 0.035 and P = 0.001, respectively). Dryness was the most common subjective complaint in both groups; however, it was more severe in AEO, especially on the second day (P = 0.023).

conclusionsDespite the healing effects of AEO in burn wounds, petrolatum was more effective than AEO in post-laser wound.

Indexed as

AcneArnebiaLaserTraditional MedicineWound Healing

Identifiers

PMID25558382
PMCPMC4270663
OpenAlexW2135084894

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.