ReviewEvolutionary applications2014
Evolutionary rescue: linking theory for conservation and medicine.
Review in Evolutionary applications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed.
- Extinction vortices are driven more by a shortage of beneficial mutations than by deleterious mutation accumulation.bioRxiv : the preprint server for biology · 2026Article
- Article
- "Excluded phenotypes" restrict genetic paths toward adaptation in declining populations.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The role of environmental stress in promoting mutators through evolutionary rescue: quantitative predictions.Genetics · 2025Article
- Article
- The speed of vaccination rollout and the risk of pathogen adaptation.Journal of the Royal Society, Interface · 2025Article
- Mutualism breakdown underpins evolutionary rescue in an obligate cross-feeding bacterial consortium.Nature communications · 2025Article
- Meeting Report on the Symposium "Evolutionary Applications" at the 3rd Joint Congress on Evolutionary Biology.Evolutionary applications · 2025Article
- Impacts of limits to adaptation on population and community persistence in a changing environment.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Temperature dependence of the mutation rate towards antibiotic resistance.JAC-antimicrobial resistance · 2024Article
- Demographic feedbacks during evolutionary rescue can slow or speed adaptive evolution.Proceedings. Biological sciences · 2024Article
- Evolutionary rescue on genotypic fitness landscapes.Journal of the Royal Society, Interface · 2023Article
- Evolutionary rescue in a fluctuating environment: periodic versus quasi-periodic environmental changes.Proceedings. Biological sciences · 2023Article
- Stackelberg evolutionary game theory: how to manage evolving systems.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- How does genetic architecture affect eco-evolutionary dynamics? A theoretical perspective.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Surviving environmental change: when increasing population size can increase extinction risk.Proceedings. Biological sciences · 2022Article
- Maximizing value of genetic sequence data requires an enabling environment and urgency.Global food security · 2022Article
- The recent evolutionary rescue of a staple crop depended on over half a century of global germplasm exchange.Science advances · 2022Article
- Ecological and Evolutionary Implications of Microbial Dispersal.Frontiers in microbiology · 2022Review
- Avoiding extinction under nonlinear environmental change: models of evolutionary rescue with plasticity.Biology letters · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evolutionary responses that rescue populations from extinction when drastic environmental changes occur can be friend or foe. The field of conservation biology is concerned with the survival of species in deteriorating global habitats. In medicine, in contrast, infected patients are treated with chemotherapeutic interventions, but drug resistance can compromise eradication of pathogens. These contrasting biological systems and goals have created two quite separate research communities, despite addressing the same central question of whether populations will decline to extinction or be rescued through evolution. We argue that closer integration of the two fields, especially of theoretical understanding, would yield new insights and accelerate progress on these applied problems. Here, we overview and link mathematical modelling approaches in these fields, suggest specific areas with potential for fruitful exchange, and discuss common ideas and issues for empirical testing and prediction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.