ArticleObesity (Silver Spring, Md.)2015
Associations among pericolonic fat, visceral fat, and colorectal polyps on CT colonography.
Article in Obesity (Silver Spring, Md.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 9 citations in OpenAlex.
- Identification of theAnimal biotechnology · 2024Article
- Fully automated segmentation and quantification of visceral and subcutaneous fat at abdominal CT: application to a longitudinal adult screening cohort.The British journal of radiology · 2018Article
- Progress in Fully Automated Abdominal CT Interpretation.AJR. American journal of roentgenology · 2016Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveTo determine the association between pericolonic fat and colorectal polyps using CT colonography (CTC).
methodsA total of 1169 patients who underwent CTC and optical colonoscopy on the same day were assessed. Pericolonic fat was measured on CTC in a band surrounding the colon. Visceral adipose tissue volume was measured at the L2-L3 levels. Student's t-tests, odds ratio, logistic regression, binomial statistics, and weighted kappa were performed to ascertain associations with the incidence of colorectal polyps.
resultsPericolonic fat volume fractions (PFVF) were 61.5 ± 11.0% versus 58.1 ± 11.5%, 61.6 ± 11.1% versus 58.7 ± 11.5%, and 62.4 ± 10.6% versus 58.8 ± 11.5% for patients with and without any polyps, adenomatous polyps, and hyperplastic polyps, respectively (P<0.0001). Similar trends were observed when examining visceral fat volume fractions (VFVF). When patients were ordered by quintiles of PFVF or VFVF, there were 2.49-, 2.19-, and 2.39-fold increases in odds ratio for the presence of any polyp, adenomatous polyps, or hyperplastic polyps from the first to the fifth quintile for PFVF and 1.92-, 2.00-, and 1.71-fold increases in odds ratio for VFVF. Polyps tended to occur more commonly in parts of the colon that had more PFVF than the spatially adjusted average for patients in the highest quintile of VFVF.
conclusionsPericolonic fat accumulations, like visceral fat, are correlated with an increased risk of adenomatous and hyperplastic polyps.
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