ArticleJournal of the American Geriatrics Society2015
The Pittsburgh Fatigability scale for older adults: development and validation.
Article in Journal of the American Geriatrics Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 121 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Value Affirmation Intervention for Physical Symptoms and Medication Adherence in Breast Cancer Patients Taking Aromatase Inhibitors
Fasting to Provide Energy Needed to Help Adults in Need of Cognitive Enhancement (FASTING ENHANCE)
Arlington Longitudinal Optimal Healthy Aging Study (ALOHA)
Who cites it
121 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence of fatigue and perceived fatigability in older adults: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Measurement properties of instruments to measure the fatigue domain of vitality capacity in community-dwelling older people: an umbrella review of systematic reviews and meta-analysis.Age and ageing · 2023Pooled it
- The "Reducing Inflammation for Greater Health Trial (RIGHT)" Study-Concept, Rationale, and Design.Journal of the American Geriatrics Society · 2026Trial
- Exploratory functional and quality of life outcomes with daily consumption of the ketone ester bis-octanoyl (R)-1,3-butanediol in healthy older adults: a randomized, parallel arm, double-blind, placebo-controlled study.The Journal of frailty & aging · 2025Trial
- Effect of Hearing Intervention Versus Health Education Control on Fatigue: A Secondary Analysis of the ACHIEVE Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Trial
- A multidomain lifestyle intervention to maintain optimal cognitive functioning in Dutch older adults-study design and baseline characteristics of the FINGER-NL randomized controlled trial.Alzheimer's research & therapy · 2024Trial
- Effect of Thyroid Hormone Therapy on Fatigability in Older Adults With Subclinical Hypothyroidism: A Nested Study Within a Randomized Placebo-Controlled Trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Trial
- Impact of Baseline Fatigue on a Physical Activity Intervention to Prevent Mobility Disability.Journal of the American Geriatrics Society · 2020Trial
- Trial
- Lower-Extremity Torque Capacity and Physical Function in Mobility-Limited Older Adults.The journal of nutrition, health & aging · 2019Trial
- Neural correlates of perceived physical and mental fatigability in older adults: A pilot study.Experimental gerontology · 2019Trial
- Psychobiological and Metabolic Correlates of Time Perception in Humans: An Exploratory Study.Psychophysiology · 2026Article
- Baseline Plasma Growth-differentiation Factor 15 and Recovery of Physical Function Following Total Knee Replacement in the Study of Physical Resilience and Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Fatigue, muscle fatigability, and the Hallmarks of Aging: a narrative review.The journal of nutrition, health & aging · 2026Review
- A combined progressive muscle relaxation and walking intervention for adults with end-stage kidney disease receiving hemodialysis (Contemporary clinical trials communications · 2026Article
- Evaluation of the construct validity of the Michigan Fatigability Index (MIFI) short forms: a cross-sectional survey study.Journal of patient-reported outcomes · 2026Article
- The right tool for the job: a comparative psychometric analysis of commonly used perceived fatigue and fatigability measures in multiple sclerosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Psychometric properties of the Pittsburgh Fatigability Scale for assessing physical and mental fatigability in Brazilian older adults (PFS-Brasil).Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026Article
- Loneliness and sarcopenia in aged care: the mediating role of fatigability.Innovation in aging · 2026Article
- The relationship between sleep and fatigue within community-residing older individuals aged 60 years or above in regional China.Frontiers in public health · 2026Article
61 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
objectivesTo describe the development of the Pittsburgh Fatigability Scale (PFS) and establish its reliability and concurrent and convergent validity against performance measures.
designCross-sectional.
settingUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
participantsScale development sample: 1,013 individuals aged 60 and older from two registries; validation sample: 483 adults aged 60 and older from the Baltimore Longitudinal Study of Aging (BLSA). MEASUREMENTS: The scale development sample and BLSA participants self-administered an initial 26-item perceived fatigability scale. BLSA participants also completed measures of performance fatigability (perceived exertion from a standard treadmill task and performance deterioration from a fast-paced long-distance corridor walk), a 6-m usual-paced corridor walk, and five timed chair stands.
resultsPrincipal components analysis with varimax rotation reduced the 26-item scale to the 10-item PFS. The PFS showed strong internal consistency (Cronbach's alpha 0.88) and excellent test-retest reliability (intraclass correlation 0.86). In the validation sample, PFS scores, adjusted for age, sex, and race, were greater for those with high performance fatigability, slow gait speed, worse physical function, and lower fitness, with differences between high and low fatigability ranging from 3.2 to 5.1 points (P < .001).
conclusionThe 10-item PFS physical fatigability score is a valid and reliable measure of perceived fatigability in older adults and can serve as an adjunct to performance-based fatigability measures for identifying older adults at risk of mobility limitation in clinical and research settings.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.