ArticleNature communications2015
Optical focusing deep inside dynamic scattering media with near-infrared time-reversed ultrasonically encoded (TRUE) light.
Article in Nature communications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
77 citing papers in PubMed.
- Focusing scattered light through live tissue with channel-selected wavefront shaping.Biomedical optics express · 2026Article
- Quantum-inspired computational wavefront shaping enables turbulence-resilient distributed aperture synthesis imaging.Science advances · 2025Article
- Synergistic Effects of Non-Ionizing Radiation in the Targeted Modification of Living Tissues.International journal of molecular sciences · 2025Review
- Optical phased arrays for wavefront shaping in forward scattering media.Nanophotonics (Berlin, Germany) · 2025Article
- All-optical phase conjugation using diffractive wavefront processing.Nature communications · 2024Article
- Photobiomodulation Therapy on Brain: Pioneering an Innovative Approach to Revolutionize Cognitive Dynamics.Cells · 2024Review
- Improving the spatial resolution and signal-to-noise ratio of ultrasound switchable fluorescence imaging.Journal of biophotonics · 2024Article
- Single-shot digital optical fluorescence phase conjugation through forward multiple-scattering samples.Science advances · 2024Article
- Single-pixel transmission matrix recovery via two-photon fluorescence.Science advances · 2024Article
- Performance enhancement in wavefront shaping of multiply scattered light: a review.Journal of biomedical optics · 2024Review
- Introducing the Special Issue Honoring Lihong V. Wang, Pioneer in Biomedical Optics.Journal of biomedical optics · 2024Article
- Tutorial on compressed ultrafast photography.Journal of biomedical optics · 2024Review
- High-gain and high-speed wavefront shaping through scattering media.Nature photonics · 2023Article
- Acousto-Optics: Recent Studies and Medical Applications.Biosensors · 2023Review
- High-speed single-exposure time-reversed ultrasonically encoded optical focusing against dynamic scattering.Science advances · 2022Article
- Wavefront shaping: A versatile tool to conquer multiple scattering in multidisciplinary fields.Innovation (Cambridge (Mass.)) · 2022Review
- Comparison of contrast-to-noise ratios of different detection methods in ultrasound optical tomography.Biomedical optics express · 2022Article
- Optophysiology: Illuminating cell physiology with optogenetics.Physiological reviews · 2022Review
- Enhance the delivery of light energy ultra-deep into turbid medium by controlling multiple scattering photons to travel in open channels.Light, science & applications · 2022Article
- Quantitative chemical sensing of drugs in scattering media with Bessel beam Raman spectroscopy.Biomedical optics express · 2022Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Focusing light deep inside living tissue has not been achieved despite its promise to play a central role in biomedical imaging, optical manipulation and therapy. To address this challenge, internal-guide-star-based wavefront engineering techniques--for example, time-reversed ultrasonically encoded (TRUE) optical focusing--were developed. The speeds of these techniques, however, were limited to no greater than 1 Hz, preventing them from in vivo applications. Here we improve the speed of optical focusing deep inside scattering media by two orders of magnitude, and focus diffuse light inside a dynamic scattering medium having a speckle correlation time as short as 5.6 ms, typical of living tissue. By imaging a target, we demonstrate the first focusing of diffuse light inside a dynamic scattering medium containing living tissue. Since the achieved focusing speed approaches the tissue decorrelation rate, this work is an important step towards in vivo deep tissue noninvasive optical imaging, optogenetics and photodynamic therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.