Evidence map›Paper›PMID 25556771›Full record

ArticleScientific reports2015

MLST-based inference of genetic diversity and population structure of clinical Klebsiella pneumoniae, China.

Chenyi Guo, Xianwei Yang, Yarong Wu, Huiying Yang, Yanping Han, Ruifu Yang, Liangping Hu, Yujun Cui, Dongsheng Zhou

Abstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Molecular Epidemiology of Carbapenem-ResistantInfection and drug resistance · 2026
    Article
  3. Article
  4. Article
  5. Transcriptomic and phenotype analysis revealed the role ofFrontiers in cellular and infection microbiology · 2023
    Article
  6. Article
  7. Surveillance Study ofAntibiotics (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Article
  10. Hypervirulent Klebsiella pneumoniae.Clinical microbiology reviews · 2019
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chenyi GuoConsulting Center of Biomedical Statistics, Beijing 100850, China.
Xianwei YangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Yarong WuState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Huiying YangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Yanping HanState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Ruifu YangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Liangping HuConsulting Center of Biomedical Statistics, Beijing 100850, China.
Yujun CuiState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Dongsheng ZhouState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multilocus sequence typing was applied to a collection of 327 clinical isolates of Klebsiella pneumoniae from China, which was proven to be a good representative of the global diversity of K. pneumoniae. Three lineages L1 to L3 are presented in the population with limited genetic flow across different lineages. However, extremely high levels of recombination can be observed within lineages to the extent at which the alleles are associated almost randomly. Lineages L2 and L3 most likely represent highly specific subgroups of less-virulent K. pneumoniae with modified metabolic networks, while lineage L1 contains not only hypervirulent clones with massive acquisition of virulent genes but also 'primitive and intermediate forms' during evolution of hypervirulent K. pneumoniae.

Indexed as

Genes, BacterialGenetic VariationAllelesBacterial ProteinsChinaCodon, NonsenseCytochrome P-450 Enzyme SystemGenetic LinkageGenetic LociGenotypeIntramolecular OxidoreductasesKlebsiella pneumoniaeMultilocus Sequence TypingPhylogenyBacterial ProteinsCodon, NonsenseCytochrome P-450 Enzyme SystemIntramolecular Oxidoreductasesprostacyclin synthetase

Identifiers

PMID25556771
PMCPMC5154592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.