Evidence map›Paper›PMID 25556602›Full record

ReviewDeutsches Arzteblatt international2014

The diagnosis of chronic obstructive pulmonary disease.

Rainer Burkhardt, Wulf Pankow

Abstract readReview
In one paragraph

Review in Deutsches Arzteblatt international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. The Differential Diagnosis of Dyspnea.Deutsches Arzteblatt international · 2016
    Review
  11. Review
  12. Review
  13. Diagnosis is difficult.Deutsches Arzteblatt international · 2015
    Article
  14. In reply.Deutsches Arzteblatt international · 2015
    Article
  15. Occupational preventive measures.Deutsches Arzteblatt international · 2015
    Article
  16. The preserve of primary care physicians.Deutsches Arzteblatt international · 2015
    Article
  17. Article
  18. Article
  19. The Impact ofIn vivo (Athens, Greece)
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Rainer BurkhardtLower Saxony State Association of Statutory Health Insurance Physicians, Office Oldenburg, Vivantes Klinikum Berlin-Neukölln, Department of Internal Medicine, Pneumology, and Infectious Diseases.
Wulf Pankow

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEstimates of the prevalence of chronic obstructive pulmonary disease (COPD) in Germany range from 1.9% to 13.2%, depending on the population studied and the investigative methods used. About 30% of all patients already have severe airway obstruction by the time the condition is diagnosed.

methodsReview of pertinent literature retrieved by a selective search, including current guidelines and textbooks.

resultsSmoking is the main risk factor for COPD. The diagnosis is based on characteristic symptoms that patients at risk should be actively asked about-cough, dyspnea, diminished physical reserve, and frequent airway infections-together with abnormal pulmonary function tests. Spirometry usually suffices to document impaired air flow. The clinical evaluation and the treatment strategy are based on the severity of airway obstruction and dyspnea, and the frequency of exacerbations. According to a European study, dyspnea is present in 73% of persons with severe COPD, expectoration in 64%, cough in 59%, and wheezing in 42%. Asthma, congestive heart failure, and interstitial lung disease are the main differential diagnoses.

conclusionCOPD may begin with symptoms that are only mild at first even in a longstanding smoker. The available diagnostic techniques need better prospective validation with respect to relevant endpoints, including mortality, symptom progression, quality of life, and frequency of exacerbations.

Indexed as

Early DiagnosisEvidence-Based MedicineHumansPhysical ExaminationPulmonary Disease, Chronic ObstructiveRespiratory Function TestsRisk AssessmentSmokingTomography, X-Ray Computed

Identifiers

PMID25556602
PMCPMC4284520

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.