Evidence map›Paper›PMID 25556205›Full record

ArticleAJNR. American journal of neuroradiology2015

Association of superior oblique muscle volumes with the presence or absence of the trochlear nerve on high-resolution MR imaging in congenital superior oblique palsy.

H K Yang, D S Lee, J H Kim, J-M Hwang

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Functional Anatomy of Ocular Counter-Rolling in Superior Oblique Palsy.Investigative ophthalmology & visual science · 2025
    Article
  4. Surgical Management of Masquerading Superior Oblique Palsy.American journal of ophthalmology · 2025
    Article
  5. High-Resolution 7T MR Imaging of the Trochlear Nerve.AJNR. American journal of neuroradiology · 2023
    Article
  6. Article
  7. Masquerading Superior Oblique Palsy.American journal of ophthalmology · 2022
    Article
  8. Association of lateral rectus muscle volume and ocular motility with the abducens nerve in Duane's retraction syndrome.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. The influence of ocular sighting dominance on Fundus torsion in patients with unilateral congenital superior oblique palsy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2017
    Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

H K YangFrom the Departments of Ophthalmology (H.K.Y., D.S.L., J.-M.H.).
D S LeeFrom the Departments of Ophthalmology (H.K.Y., D.S.L., J.-M.H.).
J H KimRadiology (J.H.K.), Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. hjm@snu.ac.kr jaehkim@snubh.org.
J-M HwangFrom the Departments of Ophthalmology (H.K.Y., D.S.L., J.-M.H.) hjm@snu.ac.kr jaehkim@snubh.org.
Research Institute of Radiology · BYHospital San Juan de Dios · CLSeoul National University Bundang Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeCongenital superior oblique palsy is known to relate to trochlear nerve absence and a variable degree of superior oblique muscle hypoplasia. The purpose of this study was to determine whether superior oblique muscle volume predicts trochlear nerve absence in congenital superior oblique palsy. MATERIALS AND

methodsA retrospective study of high-resolution MR imaging to evaluate the presence of the trochlear nerve and to measure superior oblique muscle areas and volumes with the image analysis tools of a PACS was performed in 128 consecutive patients with unilateral congenital superior oblique palsy and 34 age-matched healthy controls.

resultsOf the 128 patients with congenital superior oblique palsy, 88 had an ipsilateral trochlear nerve absence (absent group) and 40 had both trochlear nerves (present group). In patients with congenital superior oblique palsy, the paretic side superior oblique muscle volume was significantly smaller compared with the normal side only in the absent group (P < .001). The left and right side superior oblique muscle volumes were not significantly different in controls (P = .750), and the paretic and normal side superior oblique muscle volumes were not significantly different in the present group (P = .536). The cutoff value of the paretic/normal side superior oblique muscle volume ratio for diagnosing trochlear nerve absence was ≤0.75 (sensitivity 98.9%, specificity 95.0%) in patients with congenital superior oblique palsy.

conclusionsThe ratio of paretic/normal side superior oblique muscle area and volume has an excellent predictability in diagnosing trochlear nerve absence in congenital superior oblique palsy.

Indexed as

AdultAgedFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedOculomotor MusclesRetrospective StudiesTrochlear NerveTrochlear Nerve DiseasesYoung Adult

Identifiers

PMID25556205
PMCPMC7964309
OpenAlexW2128806430

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.