Evidence map›Paper›PMID 25554998›Full record

ArticleChemical communications (Cambridge, England)2015

Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophore.

Ziqing Qian, Patrick G Dougherty, Dehua Pei

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Review
  2. ThebioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Bismuth-Cyclized Cell-Penetrating Peptides.Molecular pharmaceutics · 2024
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ziqing QianDepartment of Chemistry and Biochemistry, The Ohio State University, 484 West 12th Avenue, Columbus, OH 43210, USA. pei.3@osu.edu.
Patrick G Dougherty
Dehua Pei

Funding

Recognition and Catalysis of Phosphotyrosyl ProteinsR01GM062820 · NIGMS · OHIO STATE UNIVERSITY · PI PEI, DEHUA · 2003 to 2015
$3.2M
Substrate Profiling of Protein Tyrosine PhosphatasesR01CA132855 · NCI · OHIO STATE UNIVERSITY · PI PEI, DEHUA · 2009 to 2013
$1.3M
Cyclic Cell-Penetrating PeptidesR01GM110208 · NIGMS · OHIO STATE UNIVERSITY · PI PEI, DEHUA · 2014 to 2016
$980k
NCI NIH HHS R01 CA132855NIGMS NIH HHS GM062820NIGMS NIH HHS GM110208NIGMS NIH HHS R01 GM062820NIGMS NIH HHS R01 GM110208
6 · The paper itself

Abstract

We report a simple, effective method to assess the cytosolic delivery efficiency and kinetics of cell-penetrating peptides using a pH-sensitive fluorescent probe, naphthofluorescein.

Indexed as

Cell-Penetrating PeptidesCytosolFlow CytometryFluoresceinFluoresceinsFluorescent DyesHeLa CellsHumansHydrogen-Ion ConcentrationKineticsProtein TransportSpectrometry, FluorescenceCell-Penetrating PeptidesFluoresceinFluoresceinsFluorescent Dyesnaphthofluorescein

Identifiers

PMID25554998
PMCPMC4550085

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.