Evidence map›Paper›PMID 25554970›Full record

ArticleJournal of biomedical optics2015

Shear wave elastography using amplitude-modulated acoustic radiation force and phase-sensitive optical coherence tomography.

Thu-Mai Nguyen, Bastien Arnal, Shaozhen Song, Zhihong Huang, Ruikang K Wang, Matthew O'Donnell

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026
    Review
  2. Article
  3. Biomedical optics express · 2022
    Article
  4. Article
  5. Introduction to optical coherence elastography: tutorial.Journal of the Optical Society of America. A, Optics, image science, and vision · 2022
    Article
  6. Wave-based optical coherence elastography: The 10-year perspective.Progress in biomedical engineering (Bristol, England) · 2022
    Article
  7. Article
  8. Article
  9. Corneal stromal stem cells restore transparency after NStem cells translational medicine · 2020
    Article
  10. Article
  11. Article
  12. Experimental biology and medicine (Maywood, N.J.) · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thu-Mai NguyenUniversity of Washington, Department of Bioengineering, 3720 15th Avenue NE, P.O. Box 355013, Seattle, Washington 98105, United States.
Bastien ArnalUniversity of Washington, Department of Bioengineering, 3720 15th Avenue NE, P.O. Box 355013, Seattle, Washington 98105, United States.
Shaozhen SongUniversity of Washington, Department of Bioengineering, 3720 15th Avenue NE, P.O. Box 355013, Seattle, Washington 98105, United StatesbUniversity of Dundee, School of Engineering, Departments of Physics and Mathematics, Fulton Building, Dundee DD1 4HN, Un.
Zhihong HuangUniversity of Dundee, School of Engineering, Departments of Physics and Mathematics, Fulton Building, Dundee DD1 4HN, United Kingdom.
Ruikang K WangUniversity of Washington, Department of Bioengineering, 3720 15th Avenue NE, P.O. Box 355013, Seattle, Washington 98105, United StatescUniversity of Washington, Department of Ophthalmology, 325 9th Avenue, Seattle, Washington 98104, United States.
Matthew O'DonnellUniversity of Washington, Department of Bioengineering, 3720 15th Avenue NE, P.O. Box 355013, Seattle, Washington 98105, United States.

Funding

OPTICAL MICROANGIOGRAHY OF CEREBROVASCULAR PERFUSIONR01HL093140 · NHLBI · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2008 to 2017
$4.2M
Volumetric imaging of blood perfusion and tissue morphology in the cochleaR01DC010201 · NIDCD · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2009 to 2013
$2.2M
Sensitive tumor detection with magnetomotive imagingR01CA170734 · NCI · UNIVERSITY OF WASHINGTON · PI GAO, XIAOHU · 2012 to 2015
$1.8M
Non-invasive trapping and imaging of circulating tumor cells in the peripheral vaR01EB016034 · NIBIB · UNIVERSITY OF WASHINGTON · PI O'DONNELL, MATTHEW · 2013 to 2016
$1.7M
Label-free optical imaging of 3D structural and functional microcirculationsR01EB009682 · NIBIB · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2009 to 2012
$1.7M
NCI NIH HHS R01 CA170734NCI NIH HHS R01CA170734NHLBI NIH HHS R01 HL093140NHLBI NIH HHS R01HL093140NIBIB NIH HHS NIH RO1EB016034NIBIB NIH HHS R01 EB009682NIBIB NIH HHS R01EB009682NIBIB NIH HHS R01 EB016034NIDCD NIH HHS R01 DC010201NIDCD NIH HHS R01DC010201
6 · The paper itself

Abstract

Investigating the elasticity of ocular tissue (cornea and intraocular lens) could help the understanding and management of pathologies related to biomechanical deficiency. In previous studies, we introduced a setup based on optical coherence tomography for shear wave elastography (SWE) with high resolution and high sensitivity. SWE determines tissue stiffness from the propagation speed of shear waves launched within tissue. We proposed acoustic radiation force to remotely induce shear waves by focusing an ultrasound (US) beam in tissue, similar to several elastography techniques. Minimizing the maximum US pressure is essential in ophthalmology for safety reasons. For this purpose, we propose a pulse compression approach. It utilizes coded US emissions to generate shear waves where the energy is spread over a long emission, and then numerically compressed into a short, localized, and high-energy pulse. We used a 7.5-MHz single-element focused transducer driven by coded excitations where the amplitude is modulated by a linear frequency-swept square wave (1 to 7 kHz). An inverse filter approach was used for compression. We demonstrate the feasibility of performing shear wave elastography measurements in tissue-mimicking phantoms at low US pressures (mechanical index < 0.6)

Indexed as

AnimalsCorneaElasticity Imaging TechniquesEquipment DesignPhantoms, ImagingSignal-To-Noise RatioSwineTomography, Optical Coherence

Identifiers

PMID25554970
PMCPMC4282275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.