Evidence map›Paper›PMID 25554815›Full record

ArticlePediatrics2015

Early weight loss nomograms for exclusively breastfed newborns.

Valerie J Flaherman, Eric W Schaefer, Michael W Kuzniewicz, Sherian X Li, Eileen M Walsh, Ian M Paul

Registry-linked trialAbstract read
In one paragraph

Article in Pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04025827 (Weight Patterns in the Month After Birth), which is not on this map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04025827 completednot on this mapstarted 2019, after this paper: background citation

Weight Patterns in the Month After Birth: Relationship With Dietary Intake

TypeobservationalSponsorUniversity of California, San FranciscoRan2019 to 2021Enrolled741ConditionsStunting, Wasting, Undernutrition, Feeding PatternsArmsDietary intake
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Postnatal maximal weight loss, fluid administration, and outcomes in extremely preterm newborns.Journal of perinatology : official journal of the California Perinatal Association · 2022
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  9. Stochastic vibration and early weight growth in opioid-exposed newborns: a randomized trial.Journal of perinatology : official journal of the California Perinatal Association · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Valerie J FlahermanDepartments of Pediatrics, and Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, California; flahermanv@peds.ucsf.edu.
Eric W SchaeferDepartments of Public Health Sciences, and.
Michael W KuzniewiczDepartments of Pediatrics, and Division of Research, Kaiser Permanente, Oakland, California.
Sherian X LiDivision of Research, Kaiser Permanente, Oakland, California.
Eileen M WalshDivision of Research, Kaiser Permanente, Oakland, California.
Ian M PaulDepartments of Public Health Sciences, and Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania; and.

Funding

Improving breastfeeding outcomes by interventions targeted toward at-risk infantsK23HD059818 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FLAHERMAN, VALERIE JANE · 2009 to 2013
$591k
NICHD NIH HHS K23 HD059818PHS HHS R40 MC 26811
6 · The paper itself

Abstract

backgroundThe majority of newborns are exclusively breastfed during the birth hospitalization, and weight loss is nearly universal for these neonates. The amount of weight lost varies substantially among newborns with higher amounts of weight loss increasing risk for morbidity. No hour-by-hour newborn weight loss nomogram exists to assist in early identification of those on a trajectory for adverse outcomes.

methodsFor 161 471 term, singleton neonates born at ≥36 weeks' gestation at Northern California Kaiser Permanente hospitals in 2009-2013, data were extracted from the birth hospitalization regarding delivery mode, race/ethnicity, feeding type, and weights from electronic records. Quantile regression was used to create nomograms stratified by delivery mode that estimated percentiles of weight loss as a function of time among exclusively breastfed neonates. Weights measured subsequent to any nonbreastmilk feeding were excluded.

resultsAmong this sample, 108 907 newborns had weights recorded while exclusively breastfeeding with 83 433 delivered vaginally and 25 474 delivered by cesarean. Differential weight loss by delivery mode was evident 6 hours after delivery and persisted over time. Almost 5% of vaginally delivered newborns and >10% of those delivered by cesarean had lost ≥10% of their birth weight 48 hours after delivery. By 72 hours, >25% of newborns delivered by cesarean had lost ≥10% of their birth weight.

conclusionsThese newborn weight loss nomograms demonstrate percentiles for weight loss by delivery mode for those who are exclusively breastfed. The nomograms can be used for early identification of neonates on a trajectory for greater weight loss and related morbidities.

Indexed as

Breast FeedingNomogramsWeight LossAge FactorsBirth WeightHumansInfant, Newbornbreastfeedinginfantlactationnewbornweight loss

Identifiers

PMID25554815
PMCPMC4279066

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.