Evidence map›Paper›PMID 25554730›Full record

ArticleFrontiers in biology2014

RNA-binding proteins in pluripotency, differentiation, and reprogramming.

Diana Guallar, Jianlong Wang

Abstract read
In one paragraph

Article in Frontiers in biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Single-cell RNA profiling ofFrontiers in cellular and infection microbiology · 2022
    Article
  10. Primordial Germ Cell Development in the Poeciliid,Frontiers in cell and developmental biology · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. Regulation of pluripotency and reprogramming by RNA binding proteins.Current topics in developmental biology · 2020
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Post-transcriptional regulation of the pluripotent state.Current opinion in genetics & development · 2017
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Diana GuallarThe Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA ; Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Jianlong WangThe Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA ; Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA ; The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Icahn School of Medicine at Mount Sinai · US

Funding

Oct4 and epigenetic regulation of stem cell pluripotencyR01GM095942 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WANG, JIANLONG · 2011 to 2015
$1.6M
NIGMS NIH HHS R01 GM095942
6 · The paper itself

Abstract

Embryonic stem cell maintenance, differentiation, and somatic cell reprogramming require the interplay of multiple pluripotency factors, epigenetic remodelers, and extracellular signaling pathways. RNA-binding proteins (RBPs) are involved in a wide range of regulatory pathways, from RNA metabolism to epigenetic modifications. In recent years we have witnessed more and more studies on the discovery of new RBPs and the assessment of their functions in a variety of biological systems, including stem cells. We review the current studies on RBPs and focus on those that have functional implications in pluripotency, differentiation, and/or reprogramming in both the human and mouse systems.

Indexed as

differentiationembryonic stem celllncRNApluripotencyRNA-binding proteinsomatic cell reprogramming

Identifiers

PMID25554730
PMCPMC4279953
OpenAlexW2062562832

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.