ReviewFrontiers in bioscience (Elite edition)2015
Current strategies and challenges in engineering a bioartificial kidney.
Review in Frontiers in bioscience (Elite edition), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Contemporary Perspectives on Chronic Renal Disorders.Chronic diseases and translational medicine · 2025Review
- Feasibility of an implantable bioreactor for renal cell therapy using silicon nanopore membranes.Nature communications · 2023Article
- Cell and gene therapy for kidney disease.Nature reviews. Nephrology · 2023Review
- Capturing effects of blood flow on the transplanted decellularized nephron with intravital microscopy.Scientific reports · 2023Article
- Advances in hemodialysis therapy.Faculty reviews · 2023Review
- Powering Implantable and Ingestible Electronics.Advanced functional materials · 2021Article
- Mechanical characterization of native and sugar-modified decellularized kidneys.Journal of the mechanical behavior of biomedical materials · 2021Article
- Role of Artificial Intelligence in Kidney Disease.International journal of medical sciences · 2020Review
- Progress in the Development and Challenges for the Use of Artificial Kidneys and Wearable Dialysis Devices.Kidney diseases (Basel, Switzerland) · 2019Review
- Fabrication of Kidney Proximal Tubule Grafts Using Biofunctionalized Electrospun Polymer Scaffolds.Macromolecular bioscience · 2019Article
- Engineering molecular imaging strategies for regenerative medicine.Bioengineering & translational medicine · 2018Review
- A Non-woven Path: Electrospun Poly(lactic acid) Scaffolds for Kidney Tissue Engineering.Tissue engineering and regenerative medicine · 2018Article
- Original article submission: Platelet stress accumulation analysis to predict thrombogenicity of an artificial kidney.Journal of biomechanics · 2018Article
- Bioartificial Kidneys.Current stem cell reports · 2017Article
- Novel surgical techniques, regenerative medicine, tissue engineering and innovative immunosuppression in kidney transplantation.Archives of medical science : AMS · 2016Article
- A wearable artificial kidney for patients with end-stage renal disease.JCI insight · 2016Article
- Chronic Hemodialysis Therapy in the West.Kidney diseases (Basel, Switzerland) · 2015Review
- Bioengineering for Organ Transplantation: Progress and Challenges.Bioengineered · 2015Review
- Orbital Shear Stress Regulates Differentiation and Barrier Function of Primary Renal Tubular Epithelial Cells.ASAIO journal (American Society for Artificial Internal Organs : 1992)Article
- The future of the artificial kidney.Indian journal of urology : IJU : journal of the Urological Society of IndiaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Renal replacement therapy was an early pioneer in both extra-corporeal organ replacement and whole organ transplantation. Today, the success of this pioneering work is directly demonstrated in the millions of patients worldwide successfully treated with dialysis and kidney transplantation. However, there remain significant shortcomings to current treatment modalities that limit clinical outcomes and quality of life. To address these problems, researchers have turned to using cell-based therapies for the development of a bioartificial kidney. These approaches aim to recapitulate the numerous functions of the healthy kidney including solute clearance, fluid homeostasis and metabolic and endocrine functions. This review will examine the state-of-the-art in kidney bioengineering by evaluating the various techniques currently being utilized to create a bioartificial kidney. These promising new technologies, however, still need to address key issues that may limit the widespread adoption of cell therapy including cell sourcing, organ scaffolding, and immune response. Additionally, while these new methods have shown success in animal models, it remains to be seen whether these techniques can be successfully adapted for clinical treatment in humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.