Evidence map›Paper›PMID 25553357›Full record

ArticleComputers in biology and medicine2015

A leave-one-out cross-validation SAS macro for the identification of markers associated with survival.

Christel Rushing, Anuradha Bulusu, Herbert I Hurwitz, Andrew B Nixon, Herbert Pang

Abstract read
In one paragraph

Article in Computers in biology and medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christel RushingDepartment of Biostatistics and Bioinformatics & Duke Cancer Biostatistics, Duke University School of Medicine, Durham, NC, United States.
Anuradha BulusuDepartment of Biostatistics and Bioinformatics & Duke Cancer Biostatistics, Duke University School of Medicine, Durham, NC, United States.
Herbert I HurwitzDepartment of Medicine, Duke University School of Medicine, Durham, NC, United States.
Andrew B NixonDepartment of Medicine, Duke University School of Medicine, Durham, NC, United States.
Herbert PangDepartment of Biostatistics and Bioinformatics & Duke Cancer Biostatistics, Duke University School of Medicine, Durham, NC, United States; School of Public Health, Li Ka Shing Faculty of Medicine, Pok Fu Lam, Hong Kong SAR, China. Electronic address: pathwayrf@gmail.com.

Funding

Translational meta-analysis for elderly lung cancer patientsR21AG042894 · NIA · DUKE UNIVERSITY · PI PANG, HERBERT, WANG, XIAOFEI · 2013 to 2014
$373k
NIA NIH HHS R21 AG042894NIA NIH HHS R21-AG042894
6 · The paper itself

Abstract

A proper internal validation is necessary for the development of a reliable and reproducible prognostic model for external validation. Variable selection is an important step for building prognostic models. However, not many existing approaches couple the ability to specify the number of covariates in the model with a cross-validation algorithm. We describe a user-friendly SAS macro that implements a score selection method and a leave-one-out cross-validation approach. We discuss the method and applications behind this algorithm, as well as details of the SAS macro.

Indexed as

BiomarkersClinical Trials as TopicComputer SimulationPrognosisSurvival AnalysisAlgorithmsComputational BiologyHumansReproducibility of ResultsBiomarkersClinical trialsCross-validationPrognostic markersSAS macroScore selectionSurvival analysis

Identifiers

PMID25553357
PMCPMC4306627

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.