Evidence map›Paper›PMID 25552771›Full record

SynthesisBulletin of the World Health Organization2014

Effectiveness of travel restrictions in the rapid containment of human influenza: a systematic review.

Ana L P Mateus, Harmony E Otete, Charles R Beck, Gayle P Dolan, Jonathan S Nguyen-Van-Tam

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Bulletin of the World Health Organization, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04663776 (Wide Scale Monitoring for Acute Respiratory Infection Using a Mobile-Based Study Platform), which is not on this map. Cited by 62 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04663776 completednot on this mapstarted 2020, after this paper: background citation

Wide Scale Monitoring for Acute Respiratory Infection Using a Mobile-Based Study Platform

TypeobservationalSponsorBoston Children's HospitalRan2020 to 2021Enrolled16,000ConditionsCovid19, Influenza, Respiratory Tract Infections, Acute Respiratory Tract Infection
3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  7. The Evolving Policy Debate on Border Closure in Korea.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2020
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  16. Complex Interplay between Population Immunity and Viral Dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2023
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana L P MateusField Epidemiology Training Programme, Public Health England (East Midlands Office), Nottingham, England.
Harmony E OteteUniversity of Nottingham Health Protection and Influenza Research Group, Clinical Sciences Building, Nottingham City Hospital, Hucknall Road, Nottingham, NG5 1PB, England.
Charles R BeckUniversity of Nottingham Health Protection and Influenza Research Group, Clinical Sciences Building, Nottingham City Hospital, Hucknall Road, Nottingham, NG5 1PB, England.
Gayle P DolanField Epidemiology Service, Public Health England (North East Office), Newcastle upon Tyne, England .
Jonathan S Nguyen-Van-TamUniversity of Nottingham Health Protection and Influenza Research Group, Clinical Sciences Building, Nottingham City Hospital, Hucknall Road, Nottingham, NG5 1PB, England.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the effectiveness of internal and international travel restrictions in the rapid containment of influenza.

methodsWe conducted a systematic review according to the requirements of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Health-care databases and grey literature were searched and screened for records published before May 2014. Data extraction and assessments of risk of bias were undertaken by two researchers independently. Results were synthesized in a narrative form.

findingsThe overall risk of bias in the 23 included studies was low to moderate. Internal travel restrictions and international border restrictions delayed the spread of influenza epidemics by one week and two months, respectively. International travel restrictions delayed the spread and peak of epidemics by periods varying between a few days and four months. Travel restrictions reduced the incidence of new cases by less than 3%. Impact was reduced when restrictions were implemented more than six weeks after the notification of epidemics or when the level of transmissibility was high. Travel restrictions would have minimal impact in urban centres with dense populations and travel networks. We found no evidence that travel restrictions would contain influenza within a defined geographical area.

conclusionExtensive travel restrictions may delay the dissemination of influenza but cannot prevent it. The evidence does not support travel restrictions as an isolated intervention for the rapid containment of influenza. Travel restrictions would make an extremely limited contribution to any policy for rapid containment of influenza at source during the first emergence of a pandemic virus.

Indexed as

TravelCommunicable Disease ControlGlobal HealthHumansInfluenza, HumanPandemicsProgram EvaluationPublic Health PracticeTime Factors

Identifiers

PMID25552771
PMCPMC4264390

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.