Evidence map›Paper›PMID 25552613›Full record

ArticleBMJ open2014

Neural biomarkers for assessing different types of imagery in pictorial health warning labels for cigarette packaging: a cross-sectional study.

Roger D Newman-Norlund, James F Thrasher, Johann Fridriksson, William Brixius, Brett Froeliger, David Hammond, Michael K Cummings

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Adolescent Attention to Disgust Visuals in Cigarette Graphic Warning Labels.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2019
    Article
  5. Using Neuroscience to Inform Tobacco Control Policy.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Depressive symptoms and responses to cigarette pack warning labels among Mexican smokers.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Roger D Newman-NorlundDepartment of Exercise Science, University of South Carolina, Columbia, South Carolina, USA.
James F ThrasherDepartment of Health Promotion, Education and Behavior, University of South Carolina, Columbia, South Carolina, USA.
Johann FridrikssonDepartment of Health Promotion, Education and Behavior, University of South Carolina, Columbia, South Carolina, USA.
William BrixiusDepartment of Psychology, University of South Carolina, Columbia, South Carolina, USA.
Brett FroeligerDepartment of Neurosciences, Medical University of South Carolina, Charleston, South Carolina, USA Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina, USA.
David HammondUniversity of Waterloo, School of Public Health and Health Systems, Waterloo, Ontario, Canada.
Michael K CummingsMedical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina, USA.
University of South Carolina · USMedical University of South Carolina · USMUSC Hollings Cancer Center · USUniversity of Waterloo · CA

Funding

Variation in Cigarettes, Tobacco use Behaviors and Exposures in ITC CountriesP01CA138389 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI THOMPSON, MARY · 2009 to 2013
$13.4M
Neuroimaging of Nicotine Dependence, Depression and Emotion RegulationR01DA033459 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI FROELIGER, BRETT · 2012 to 2016
$1.9M
NCI NIH HHS P01 CA138389NIDA NIH HHS R01 DA033459
6 · The paper itself

Abstract

objectiveCountries around the world have increasingly adopted pictorial health warning labels (HWLs) for tobacco packages to warn consumers about smoking-related risks. Research on how pictorial HWLs work has primarily analysed self-reported responses to HWLs; studies at the neural level comparing the brain's response to different types of HWLs may provide an important complement to prior studies, especially if self-reported responses are systematically biased. In this study we characterise the brain's response to three types of pictorial HWLs for which prior self-report studies indicated different levels of efficacy.

methodsCurrent smokers rated pictorial HWLs and then observed the same HWLs during functional MRI (fMRI) scanning. Fifty 18-50-year-old current adult smokers who were free from neurological disorders were recruited from the general population and participated in the study. Demographics, smoking-related behaviours and self-reported ratings of pictorial HWL stimuli were obtained prior to scanning. Brain responses to HWLs were assessed using fMRI, focusing on a priori regions of interest.

resultsPictorial HWL stimuli elicited activation in a broad network of brain areas associated with visual processing and emotion. Participants who rated the stimuli as more emotionally arousing also showed greater neural responses at these sites.

conclusionsSelf-reported ratings of pictorial HWLs are correlated with neural responses in brain areas associated with visual and emotional processing. Study results cross-validate self-reported ratings of pictorial HWLs and provide insights into how pictorial HWLs are processed.

Indexed as

Imagery, PsychotherapyProduct LabelingAdultAnalysis of VarianceBiomarkersBrainCross-Sectional StudiesDiffusion Magnetic Resonance ImagingFemaleHumansMaleMiddle AgedPhotic StimulationTobacco ProductsYoung AdultBiomarkersPUBLIC HEALTH

Identifiers

PMID25552613
PMCPMC4281542
OpenAlexW2143046126

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.