ArticleG3 (Bethesda, Md.)2014
The evolving puzzle of autosomal versus Y-linked male determination in Musca domestica.
Article in G3 (Bethesda, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Asymmetric chromatin accessibility underlies anterior-posterior axis specification in moth fly embryos.PLoS biology · 2026Article
- Maternal inheritance of primary sex ratios in the dark-winged fungus gnat Lycoriella ingenua.Heredity · 2026Article
- Breaking anterior-posterior symmetry in the moth flybioRxiv : the preprint server for biology · 2025Article
- Evidence for a Novel X Chromosome in Termites.Genome biology and evolution · 2024Article
- Article
- Divergent evolution of male-determining loci on proto-Y chromosomes of the housefly.Nature communications · 2024Article
- Reorganization of the ancestral sex-determining regions during the evolution of trioecy in Pleodorina starrii.Communications biology · 2023Article
- Divergent evolution of genetic sex determination mechanisms along environmental gradients.Evolution letters · 2023Article
- Strong variation in frequencies of male and female determiners between neighboring housefly populations.Insect science · 2022Article
- Epistatic interactions between sex chromosomes and autosomes can affect the stability of sex determination systems.Journal of evolutionary biology · 2021Article
- Thermal tolerance and preference are both consistent with the clinal distribution of house fly proto-Y chromosomes.Evolution letters · 2021Article
- Identification of the sex chromosome system in a sand fly species, Lutzomyia longipalpis s.l.G3 (Bethesda, Md.) · 2021Article
- Evolution of sexual development and sexual dimorphism in insects.Current opinion in genetics & development · 2021Review
- Review
- Gene-Level, but Not Chromosome-Wide, Divergence between a Very Young House Fly Proto-Y Chromosome and Its Homologous Proto-X Chromosome.Molecular biology and evolution · 2021Article
- Sex Chromosome Evolution in Muscid Flies.G3 (Bethesda, Md.) · 2020Article
- Sex differences in spiders: from phenotype to genomics.Development genes and evolution · 2020Review
- Minimal Effects of Proto-Genetics · 2019Article
- Review
- The house fly Y Chromosome is young and minimally differentiated from its ancient X Chromosome partner.Genome research · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sex determination is one of the most rapidly evolving developmental pathways, but the factors responsible for this fast evolution are not well resolved. The house fly, Musca domestica, is an ideal model for studying sex determination because house fly sex determination is polygenic and varies considerably between populations. Male house flies possess a male-determining locus, the M factor, which can be located on the Y or X chromosome or any of the five autosomes. There can be a single M or multiple M factors present in an individual male, in heterozygous or homozygous condition. Males with multiple copies of M skew the sex ratio toward the production of males. Potentially in response to these male-biased sex ratios, an allele of the gene transformer, Md-tra(D), promotes female development in the presence of one or multiple M factors. There have been many studies to determine the linkage and frequency of these male determining factors and the frequency of Md-tra(D) chromosomes in populations from around the world. This review provides a summary of the information available to date regarding the patterns of distribution of autosomal, X-linked and Y-linked M factors, the relative frequencies of the linkage of M, the changes in frequencies found in field populations, and the fitness of males with autosomal M factors vs. Y-linked M. We evaluate this natural variation in the house fly sex determination pathway in light of models of the evolution of sex determination.
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