Evidence map›Paper›PMID 25552606›Full record

ArticleG3 (Bethesda, Md.)2014

Identification of new players in cell division, DNA damage response, and morphogenesis through construction of Schizosaccharomyces pombe deletion strains.

Jun-Song Chen, Janel R Beckley, Nathan A McDonald, Liping Ren, MariaSanta Mangione, Sylvia J Jang, Zachary C Elmore, Nicole Rachfall, Anna Feoktistova, Christine M Jones and 7 more

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. The power of many: when genetics met yeasts and high-throughput.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
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  15. Genes Important forGenetics · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Jun-Song ChenDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.
Janel R BeckleyDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.
Nathan A McDonaldDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.
Liping RenDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.
MariaSanta MangioneDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.
Sylvia J JangDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.
Zachary C ElmoreDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.
Nicole RachfallDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.
Anna FeoktistovaDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.
Christine M JonesDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.
Alaina H WilletDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.
Rodrigo GuillenDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.
Danny A BittonDepartment of Genetics, Evolution and Environment and UCL Cancer Institute, University College London, London WC1E 6BT, United Kingdom.
Jürg BählerDepartment of Genetics, Evolution and Environment and UCL Cancer Institute, University College London, London WC1E 6BT, United Kingdom.
Michael A JensenGenome Technology Center, Stanford University School of Medicine, Palo Alto, California 01605.
Nick RhindDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605.
Kathleen L GouldDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 kathy.gould@vanderbilt.edu.
Vanderbilt University · USUniversity College London · GBStanford University · USUniversity of Massachusetts Chan Medical School · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3M
Vanderbilt/Meharry Initiative for Minority Student DvptR25GM062459 · NIGMS · VANDERBILT UNIVERSITY · PI VELEZ EDWARDS, DIGNA R · 2002 to 2020
$10.4M
Integrated Biological Systems Training in OncologyT32CA119925 · NCI · VANDERBILT UNIVERSITY · PI Vivian Gama, William Patrick Tansey · 2008 to 2026
$7.6M
Regulation of CytokinesisR01GM101035 · NIGMS · VANDERBILT UNIVERSITY · PI GOULD, KATHLEEN L · 2012 to 2018
$2.8M
The Regulation of DNA Replication KineticsR01GM098815 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI RHIND, NICHOLAS R · 2012 to 2015
$1.3M
NCI NIH HHS T32 CA119925NIGMS NIH HHS R01 GM098815NIGMS NIH HHS R01 GM101035NIGMS NIH HHS R25 GM062459NIGMS NIH HHS T32 GM007347Wellcome Trust 095598Wellcome Trust 095598/Z/11/Z
6 · The paper itself

Abstract

Many fundamental biological processes are studied using the fission yeast, Schizosaccharomyces pombe. Here we report the construction of a set of 281 haploid gene deletion strains covering many previously uncharacterized genes. This collection of strains was tested for growth under a variety of different stress conditions. We identified new genes involved in DNA metabolism, completion of the cell cycle, and morphogenesis. This subset of nonessential gene deletions will add to the toolkits available for the study of biological processes in S. pombe.

Indexed as

Gene DeletionGenes, FungalCell DivisionDNA DamageSchizosaccharomycescell divisionDNA metabolismfission yeastgene deletionstress sensitivity

Identifiers

PMID25552606
PMCPMC4349090
OpenAlexW2113230214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.