Trial reportEuropean journal of applied physiology2015
The effect of glycogen reduction on cardiorespiratory and metabolic responses during downhill running.
Trial report in European journal of applied physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
- Effects of 120 g/h of Carbohydrates Intake during a Mountain Marathon on Exercise-Induced Muscle Damage in Elite Runners.Nutrients · 2020Trial
- Blood biomarkers, infrared thermography, and meat quality in Nellore bulls under tropical conditions.Tropical animal health and production · 2026Article
- Downhill Running: What Are The Effects and How Can We Adapt? A Narrative Review.Sports medicine (Auckland, N.Z.) · 2020Review
- Acute and Delayed Neuromuscular Alterations Induced by Downhill Running in Trained Trail Runners: Beneficial Effects of High-Pressure Compression Garments.Frontiers in physiology · 2018Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeExercise-induced muscle damage and lowered glycogen are common during heavy training periods, and may prolong recovery. We examined the effects of lowered glycogen on cardiorespiratory, metabolic and perceptual responses to downhill running.
methodsTwelve men performed two downhill runs (-12 % gradient, 12.1 ± 1.1 km h(-1)) separated by 6 weeks, under normal (NORM) and reduced glycogen (RED) conditions in a crossover design. For RED, participants performed exhaustive cycling at 60 % [Formula: see text]O2max power (95 ± 13 min) in the evening, and the next morning completed a downhill run comprising of five stages of 8 min running, with 2 min recovery (1 % gradient, 8 km h(-1)) between each stage. Expired gas, heart rate, rating of perceived exertion (RPE) and blood lactate (bLa) and glucose were measured for each stage.
resultsBlood glucose (P < 0.05) and respiratory exchange ratio (P < 0.01) were lower in RED, than NORM, throughout the downhill run. RED demonstrated higher bLa until stage Four (P < 0.05), and RPE for stages Two and Five (P < 0.05).Ventilatory equivalent of carbon dioxide output ([Formula: see text]/[Formula: see text]) was higher for stages One (P < 0.01), Two and Five (P < 0.05), and oxygen uptake ([Formula: see text] E/[Formula: see text]O2) was lower for stages Three and Four (P < 0.05) for RED.
conclusionsDownhill running with reduced glycogen, elevated fat oxidation and bLa response, and, in part, increased effort perception. The alterations in [Formula: see text] E/[Formula: see text]O2 and bLa may suggest that carbon dioxide removal was somewhat impaired.
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