ArticleJournal of clinical microbiology2015
Cost-effective pooling of DNA from nasopharyngeal swab samples for large-scale detection of bacteria by real-time PCR.
Article in Journal of clinical microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 26 citations in OpenAlex.
- Factors affecting detection and quantification of Schistosoma haematobium eggs in pooled urine samples.PLoS neglected tropical diseases · 2026Article
- Performance of Urine Reagent Test Strips in DetectingMicroorganisms · 2025Article
- Clinical sensitivity and time-to-result of a cascaded pooled testing approach for assessing the prevalence and intensity of Schistosoma haematobium infection.PLoS neglected tropical diseases · 2024Article
- Nested Group Testing Procedure.Communications in mathematics and statistics · 2022Article
- Article
- Pooled Testing Strategies for SARS-CoV-2 diagnosis: A comprehensive review.Diagnostic microbiology and infectious disease · 2021Review
- Acquisition of multidrug-resistant bacteria and encoding genes among French pilgrims during the 2017 and 2018 Hajj.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Article
- Considerations for Pooled Testing of Employees for SARS-CoV-2.Journal of occupational and environmental medicine · 2021Article
- Simple Questionnaires to Improve Pooling Strategies for SARS-CoV-2 Laboratory Testing.Annals of global health · 2020Article
- Pooling of Upper Respiratory Specimens Using a SARS-CoV-2 Real-time RT-PCR Assay Authorized for Emergency Use in Low-Prevalence Populations for High-Throughput Testing.Open forum infectious diseases · 2020Article
- Simulation of pooled-sample analysis strategies for COVID-19 mass testing.Bulletin of the World Health Organization · 2020Article
- Article
- Array testing for multiplex assays.Biostatistics (Oxford, England) · 2020Article
- Group Testing for SARS-CoV-2: Forward to the Past?PharmacoEconomics - open · 2020Article
- Article
- Regression analysis and variable selection for two-stage multiple-infection group testing data.Statistics in medicine · 2019Article
- Low prevalence of resistance genes in sheltered homeless population in Marseille, France, 2014-2018.Infection and drug resistance · 2019Article
- Group testing case identification with biomarker information.Computational statistics & data analysis · 2018Article
- Group testing regression models with dilution submodels.Statistics in medicine · 2017Article
- Electrical Detection of Pneumococcus through the Nanoparticle Decoration Method.Sensors (Basel, Switzerland) · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the potential of pooling DNA from nasopharyngeal specimens to reduce the cost of real-time PCR (RT-PCR) for bacterial detection. Lyophilization is required to reconcentrate DNA. This strategy yields a high specificity (86%) and a high sensitivity (96%). We estimate that compared to individual testing, 37% fewer RT-PCR tests are needed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.