Evidence map›Paper›PMID 25551530›Full record

ArticleThe New England journal of medicine2015

Atypical hyperplasia of the breast--risk assessment and management options.

Lynn C Hartmann, Amy C Degnim, Richard J Santen, William D Dupont, Karthik Ghosh

Abstract read
In one paragraph

Article in The New England journal of medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Guideline
  6. Trial
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  9. Review
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  13. Article
  14. The promise of artificial intelligence in diagnostic breast pathology.Virchows Archiv : an international journal of pathology · 2026
    Article
  15. Review
  16. Article
  17. Opportunities to Avoid Invasive Cancer by Diagnosis and Interception of Preneoplastic Lesions and Cancer Risk Conditions.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  18. Article
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  20. Article

66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Lynn C HartmannFrom the Departments of Oncology (L.C.H.), Surgery (A.C.D.), and Internal Medicine (K.G.), Mayo Clinic, Rochester, MN; the Department of Endocrinology and Metabolism Medicine, University of Virginia, Charlottesville (R.J.S.); and the Department of Biostatistics, Vanderbilt University, Nashville (W.D.D.).
Amy C Degnim
Richard J Santen
William D Dupont
Karthik Ghosh

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8M
Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI Felicity Enders · 1985 to 2026
$151.3M
The Role of CHFR in Tumorigenesis and Paclitaxel-Sensitivity in Breast CancerP50CA116201 · NCI · MAYO CLINIC ROCHESTER · PI PETER C LUCAS · 2005 to 2026
$49.9M
TISSUE CoreP50CA098131 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PARK, BEN HO, PIETENPOL, JENNIFER A · 2003 to 2024
$48.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Paul Calabresi Program in Clinical/Translational Research at Mayo ClinicK12CA090628 · NCI · MAYO CLINIC ROCHESTER · PI WEROHA, SARAVUT · 2001 to 2025
$19.7M
EPIDEMIOLOGY OF MOLECULAR RISK FACTORS FOR BREAST CANCERR01CA050468 · NCI · VANDERBILT UNIVERSITY · PI DUPONT, WILLIAM D · 1990 to 2011
$5.9M
NCATS NIH HHS UL1 TR000445NCI NIH HHS 1P50 CA098131NCI NIH HHS K12 CA090628NCI NIH HHS P30 CA015083NCI NIH HHS P30 CA068485NCI NIH HHS P50 CA098131NCI NIH HHS P50 CA116201NCI NIH HHS R01 CA050468
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Risk AssessmentAdultBiopsyBreastBreast NeoplasmsFemaleHumansHyperplasiaIncidenceMagnetic Resonance ImagingMastectomyMiddle AgedSelective Estrogen Receptor ModulatorsSelective Estrogen Receptor Modulators

Identifiers

PMID25551530
PMCPMC4347900

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.