ReviewSystematic reviews2014
Recovering the raw data behind a non-parametric survival curve.
Review in Systematic reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 13 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 13 syntheses or guidelines pooled it.
- Effect of Excessive Daytime Sleepiness and Long Sleep Duration on All Cause Dementia: A Systematic Review and Meta-analysis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Pooled it
- High-potency nucleos(t)ide analogues alone or plus immunoglobulin for HBV prophylaxis after liver transplantation: a meta-analysis.Hepatology international · 2023Pooled it
- Supramaximal versus gross total resection in Glioblastoma, IDH wild-type and Astrocytoma, IDH-mutant, grade 4, effect on overall and progression free survival: systematic review and meta-analysis.Journal of neuro-oncology · 2023Pooled it
- Different inhaled corticosteroid doses in triple therapy for chronic obstructive pulmonary disease: systematic review and Bayesian network meta-analysis.Scientific reports · 2022Pooled it
- Framework for the synthesis of non-randomised studies and randomised controlled trials: a guidance on conducting a systematic review and meta-analysis for healthcare decision making.BMJ evidence-based medicine · 2022Pooled it
- Systematic review and meta-analysis of tumour microsatellite-instability status as a predictor of response to fluorouracil-based adjuvant chemotherapy in colorectal cancer.International journal of colorectal disease · 2022Pooled it
- Comparisons of exacerbations and mortality among LAMA/LABA combinations in stable chronic obstructive pulmonary disease: systematic review and Bayesian network meta-analysis.Respiratory research · 2020Pooled it
- A systematic review and meta-analysis of supratotal versus gross total resection for glioblastoma.Journal of neuro-oncology · 2020Pooled it
- Pooled it
- Calorie restriction is the most reasonable anti-ageing intervention: a meta-analysis of survival curves.Scientific reports · 2018Pooled it
- Non anti-coagulant factors associated with filter life in continuous renal replacement therapy (CRRT): a systematic review and meta-analysis.BMC nephrology · 2017Pooled it
- Depressive symptoms are associated with higher rates of readmission or mortality after medical hospitalization: A systematic review and meta-analysis.Journal of hospital medicine · 2016Pooled it
- Comparisons of Efficacy and Safety between Triple (Inhaled Corticosteroid/Long-Acting Muscarinic Antagonist/Long-Acting Beta-Agonist) Therapies in Chronic Obstructive Pulmonary Disease: Systematic Review and Bayesian Network Meta-Analysis.Respiration; international review of thoracic diseasesPooled it
- Using Quadratic Programming to Reconstruct Data From Published Survival and Competing Risks Analyses.Statistics in medicine · 2026Article
- Practical methods for incorporating summary time-to-event data into meta-analysis: updated guidance.Systematic reviews · 2025Article
- Calculating the Expected Net Benefit of Sampling for Survival Data: A Tutorial and Case Study.Medical decision making : an international journal of the Society for Medical Decision Making · 2024Article
- SurvdigitizeR: an algorithm for automated survival curve digitization.BMC medical research methodology · 2024Article
- Rethinking clinical study data: why we should respect analysis results as data.Scientific data · 2022Article
- Privacy-aware multi-institutional time-to-event studies.PLOS digital health · 2022Article
- Prognostic Value of Myocardial Blush Grade in ST-elevation MI: A Systematic Review and Meta-analysis.Interventional cardiology (London, England) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundResearchers often wish to carry out additional calculations or analyses using the survival data from one or more studies of other authors. When it is not possible to obtain the raw data directly, reconstruction techniques provide a valuable alternative. Several authors have proposed methods/tools for extracting data from such curves using a digitizing software. Instead of using a digitizer to read in the coordinates from a raster image, we propose directly reading in the lines of the PostScript file of a vector image.
methodsUsing examples, and a formal error analysis, we illustrate the extent to which, with what accuracy and precision, and in what circumstances, this information can be recovered from the various electronic formats in which such curves are published. We focus on the additional precision, and elimination of observer variation, achieved by using vector-based formats rendered by PostScript, rather than the lower resolution image-based formats that have been analyzed up to now. We provide some R code to process these.
resultsIf the raster-based images are available, one can reliably recover much of the original information that seems to be 'hidden' beneath published survival curves. If the original images can be obtained as a PostScript file, the data recovered from it can then be either input into these tools or processed directly. We found that the PostScript used by Stata discloses considerably more of the data hidden behind survival curves than that generated by other statistical packages.
conclusionsWhen it is not possible to obtain the raw data from the authors, reconstruction techniques are a valuable alternative. Compared with previous approaches, one advantage of ours is that there is no observer variation: there is no need to repeat the digitization process, since the extraction is completely replicable.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.