Evidence map›Paper›PMID 25551201›Full record

SynthesisPsychosomatic medicine2015

Ethnic differences in resting heart rate variability: a systematic review and meta-analysis.

LaBarron K Hill, Dixie D Hu, Julian Koenig, John J Sollers, Gaston Kapuku, Xiaoling Wang, Harold Snieder, Julian F Thayer

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Psychosomatic medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 4 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 4 syntheses or guidelines pooled it, 173 citations in OpenAlex.

  1. Guideline
  2. Pooled it
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  10. Article
  11. Guidelines for rigor and reproducibility of heart rate variability within human cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2026
    Review
  12. Article
  13. Article
  14. Racial Discrimination-Related Interoceptive Network Disruptions: A Pathway to Disconnection.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026
    Article
  15. Article
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  20. Review

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

LaBarron K HillFrom the Center for the Study of Aging and Human Development (L.K.H.) and Department of Psychiatry (L.K.H.), Duke University Medical Center, Durham, North Carolina; Department of Psychology (D.D.H., J.K., J.F.T.), The Ohio State University, Columbus, Ohio; Department of Psychological Medicine (J.J.S.), The University of Auckland, Auckland, New Zealand; Georgia Prevention Institute (G.K., X.W., H.S.), Georgia Health Sciences University, Augusta, Georgia; Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology (H.S.), University of Groningen-University Medical Center, Groningen, the Netherlands.
Dixie D Hu
Julian Koenig
John J Sollers
Gaston Kapuku
Xiaoling Wang
Harold Snieder
Julian F Thayer
The Ohio State University · US

Funding

BEHAVIOR AND PHYSIOLOGY IN AGINGT32AG000029 · NIA · DUKE UNIVERSITY · PI Maria Marquine · 1985 to 2026
$9.3M
NIA NIH HHS 5T32AG000029-37NIA NIH HHS T32 AG000029
6 · The paper itself

Abstract

backgroundEthnic disparities in cardiovascular morbidity and mortality are widely documented in the literature. Recently, research has shown that decreased parasympathetic cardiac modulation is associated with the established and emerging risk factors for cardiovascular disease (CVD) and stroke. In consideration of the disproportionate CVD risk and disease profile of African Americans (AAs), it is plausible that decreased cardiac parasympathetic functioning may partially explain these disparities. In the present systematic review and meta-analysis, we assess the available evidence for a reliable ethnic difference in tonic vagally mediated heart rate variability (HRV), an indicator of parasympathetic cardiac modulation.

methodsA systematic literature search was conducted yielding studies comparing tonic HRV in AAs and European Americans. Adjusted standardized effect sizes (Hedges g) were calculated using a mixed-effects model, with restricted maximum likelihood estimation for 17 studies containing appropriate measures of vagally mediated HRV.

resultsMeta-analysis results suggest that AAs have greater HRV than do European Americans (Hedges g = 0.93, 95% confidence interval = 0.25-1.62), even after consideration of several covariates including health status, medication use, and subgroup stratification by sex and age.

conclusionsThese findings suggest that decreased vagally mediated HRV is not likely to account for the persistent health disparities experienced by AAs with respect to CVD risk and burden. These disparities underscore the need for continued research addressing socioethnic cardiovascular differences and the biobehavioral mechanisms involved.

Indexed as

Black or African AmericanCardiovascular DiseasesEthnicityHeart RateHumansRisk FactorsWhite People

Identifiers

PMID25551201
PMCPMC4293235
OpenAlexW1975321311

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.