ArticleJournal of diabetes and metabolic disorders2014
Changes in glycosylated haemoglobin and treatment outcomes in patients with tuberculosis in Iran: a cohort study.
Article in Journal of diabetes and metabolic disorders, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effect of glycemic control on tuberculosis treatment outcomes among patients with tuberculosis and diabetes mellitus: A systematic review and meta-analysis.Tropical medicine & international health : TM & IH · 2025Pooled it
- Pooled it
- Pooled it
- Pooled it
- TB and diabetes in Eswatini: Addressing suboptimal treatment outcomes through integrated services.PLOS global public health · 2025Article
- Article
- Glycemic control during TB treatment among Filipinos: The Starting Anti-Tuberculosis Treatment Cohort Study.PLOS global public health · 2024Article
- Article
- Longitudinal trends in glycated hemoglobin during and after tuberculosis treatment.Diabetes research and clinical practice · 2023Article
- Diabetes-Tuberculosis Care in Eswatini: A Qualitative Study of Opportunities and Recommendations for Effective Services Integration.International journal of public health · 2023Article
- Tuberculosis treatment and resulting abnormal blood glucose: a scoping review of studies from 1981 - 2021.Global health action · 2022Article
- Article
- Dysglycaemia among tuberculosis patients without known diabetes in a low-endemic setting.ERJ open research · 2022Article
- Article
- Diabetes in a TB and HIV-endemic South African population: Analysis of a virtual cohort using routine health data.PloS one · 2021Article
- Liaison of Sugar Control With Time to Sputum Culture Conversion in Multi-Drug Resistant Tuberculosis.Cureus · 2020Article
- Changes in Host Response toFrontiers in cellular and infection microbiology · 2019Review
- Screening tuberculosis patients for diabetes mellitus in a routine program setting in Kampala, Uganda: a cross-sectional study.F1000Research · 2019Article
- Stress Hyperglycemia in Patients with Tuberculosis Disease: Epidemiology and Clinical Implications.Current diabetes reports · 2018Review
- Trends in HbA1c levels and implications for diabetes screening in tuberculosis cases undergoing treatment in India.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetes mellitus (DM) affects tuberculosis (TB) treatment outcomes, mostly by increasing recurrence, mortality and treatment failure. The objectives were to determine the pattern of change in glycosylated haemoglobin (HbA1c) level in new TB patients admitted to hospital at the start and 3-months after TB treatment, and to relate the measurements at these two time intervals to whether patients successfully completed treatment.
methodsA prospective cohort study was conducted on hospitalized new TB patients at Masih Daneshvari Hospital from 2012 to 2013. All patients were tested for HbA1c at the beginning and 3 months after initiation of TB treatment. Changes in HbA1c were compared to TB treatment outcome.
resultsThere were 317 new TB cases admitted to hospital of which 158 had HbA1c at baseline and 3-months. Of these, 67 (42%) had normal values, 54 had an elevated HbA1c at either base-line or 3-months (uncertain diabetes status) and 37 (24%) had elevated HbA1c (≥6.5%) at both time points (DM). There were differences between the groups: those with DM were older, had a known history of DM and a higher prevalence of cavities on chest x-ray. There were 150 (95%) patients who successfully completed treatment with no significant differences between the groups.
conclusionThere were changes in HbA1c during the first three-months of anti-TB treatment, but these were not associated with differences in TB treatment outcomes. Transient hyperglycemia should be considered in TB patients and needs to be taken into account in planning care and management.
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