Evidence map›Paper›PMID 25550994›Full record

ReviewWorld journal of radiology2014

Functional topography of the corpus callosum investigated by DTI and fMRI.

Mara Fabri, Chiara Pierpaoli, Paolo Barbaresi, Gabriele Polonara

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 3 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 3 syntheses or guidelines pooled it, 167 citations in OpenAlex.

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  20. Subcallosal cingulate deep brain stimulation evokes two distinct cortical responses via differential white matter activation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Mara FabriMara Fabri, Chiara Pierpaoli, Paolo Barbaresi, Dipartimento di Medicina Sperimentale e Clinica, Sezione di Neuroscienze e Biologia Cellulare, Università Politecnica delle Marche, 60020 Ancona, Italy.
Chiara PierpaoliMara Fabri, Chiara Pierpaoli, Paolo Barbaresi, Dipartimento di Medicina Sperimentale e Clinica, Sezione di Neuroscienze e Biologia Cellulare, Università Politecnica delle Marche, 60020 Ancona, Italy.
Paolo BarbaresiMara Fabri, Chiara Pierpaoli, Paolo Barbaresi, Dipartimento di Medicina Sperimentale e Clinica, Sezione di Neuroscienze e Biologia Cellulare, Università Politecnica delle Marche, 60020 Ancona, Italy.
Gabriele PolonaraMara Fabri, Chiara Pierpaoli, Paolo Barbaresi, Dipartimento di Medicina Sperimentale e Clinica, Sezione di Neuroscienze e Biologia Cellulare, Università Politecnica delle Marche, 60020 Ancona, Italy.
Ministry of Education, Universities and Research · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This short review examines the most recent functional studies of the topographic organization of the human corpus callosum, the main interhemispheric commissure. After a brief description of its anatomy, development, microstructure, and function, it examines and discusses the latest findings obtained using diffusion tensor imaging (DTI) and tractography (DTT) and functional magnetic resonance imaging (fMRI), three recently developed imaging techniques that have significantly expanded and refined our knowledge of the commissure. While DTI and DTT have been providing insights into its microstructure, integrity and level of myelination, fMRI has been the key technique in documenting the activation of white matter fibers, particularly in the corpus callosum. By combining DTT and fMRI it has been possible to describe the trajectory of the callosal fibers interconnecting the primary olfactory, gustatory, motor, somatic sensory, auditory and visual cortices at sites where the activation elicited by peripheral stimulation was detected by fMRI. These studies have demonstrated the presence of callosal fiber tracts that cross the commissure at the level of the genu, body, and splenium, at sites showing fMRI activation. Altogether such findings lend further support to the notion that the corpus callosum displays a functional topographic organization that can be explored with fMRI.

Indexed as

Brain imagingCorpus callosumFunctional magnetic resonance imaging and diffusion tensor imagingInterhemispheric transferTopographic organization

Identifiers

PMID25550994
PMCPMC4278150
OpenAlexW2152338753

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.