ArticleInternational journal of clinical and experimental medicine2014
The association between multiple sclerosis and fracture risk.
Article in International journal of clinical and experimental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Comparison of postoperative pain between InterTan and proximal femoral nail anti-rotation in femoral intertrochanteric fractures: a retrospective study.American journal of translational research · 2024Article
- Mendelian randomization analysis of the causal association of bone mineral density and fracture with multiple sclerosis.Frontiers in neurology · 2022Article
- Epidemiology of hip fracture in nursing home residents with multiple sclerosis.Disability and health journal · 2018Article
- Comparative study of InterTAN and Dynamic Hip Screw in treatment of femoral intertrochanteric injury and wound.International journal of clinical and experimental medicine · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sever studies were performed to assess the association between multiple sclerosis (MS) and fracture risk. However, the results were inconsistent and inconclusive. In the present study, the possible association was investigated by a meta-analysis. Eligible articles were identified for the period up to August 2014. Pooled risk ratios (RR) with 95% confidence intervals (CI) were appropriately derived from random-effects models. Nine studies with more than 9,000,000 subjects were eligible. We found that MS was significant associated with fracture risk in overall population (OR = 1.58, 95% CI 1.36-1.84, P < 0.01). In terms of subgroup analyses by fracture sites, the associations were significant in femur (RR = 4.57, 95% CI 3.01-6.69, P < 0.01), hip (RR = 3.01, 95% CI 2.72-3.41, P < 0.01), tibia (RR = 2.72, 95% CI 2.22-3.32, P < 0.01), humerus (RR = 1.78, 95% CI 1.12-2.40, P = 0.02), pelvis (RR = 1.34, 95% CI 1.12-1.67, P < 0.01), and vertebrae (RR = 1.30, 95% CI 1.13-1.69, P < 0.01). This meta-analysis suggested that MS may be associated with fracture development.
Indexed as
Identifiers
25550949PMC4276207W2405750401What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.