ArticleInternational journal of clinical and experimental pathology2014
Multifocal canalicular adenoma of the minor labial salivary glands.
Article in International journal of clinical and experimental pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Imaging of benign salivary gland tumors: an update based on the fifth WHO classification, with a focus on rare histologic types and newly listed entities-part I.Japanese journal of radiology · 2026Review
- Canalicular Adenomas of Minor Salivary Glands: A Systematic Review of Case Reports and Case Series.Journal of clinical medicine · 2026Review
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- A case of canalicular adenoma with anemia.Journal of surgical case reports · 2022Article
- Canalicular adenoma: palatal presentation of an uncommon lesion.BMJ case reports · 2021Article
- Synchronous Multifocal Canalicular Adenomas.Head and neck pathology · 2021Article
- Canalicular adenoma of the hard palate: A rare case report.Dental research journal · 2021Article
- Analysis of the Clinical Relevance of Histological Classification of Benign Epithelial Salivary Gland Tumours.Advances in therapy · 2019Review
- Synchronous Polymorphous Adenocarcinoma and Canalicular Adenoma on the Upper Lip: An Unusual Presentation and Immunohistochemical Analysis.Head and neck pathology · 2018Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Canalicular adenoma (CA) is an uncommon benign neoplasia of salivary glands which is clinically difficult to recognise. Despite having an excellent prognosis, the histological diagnosis and clinical management of this entity can be troublesome. While the main differential diagnosis to consider is basal cell adenoma (BCA), similar histological patterns and multifocality have been observed in adenoid cystic carcinoma (ACC) and polymorphous low-grade adenocarcinoma (PLGA), both locally-aggressive malignancies which require radically different treatment to CA. An emphasis has been placed on the value of immunohistochemistry in avoiding diagnostic and surgical errors. CA is positive for AE1/AE3, CD117 and S-100 protein, and negative for p63, α-SMA, Ki 67 and vimentin. Here we discuss the case of a 61-year-old female with CA in her right upper lip, showing multifocal growth histologically. The differential diagnosis with other adenomas is discussed in addition to the role of immunohistochemical studies that can confirm the clinical and surgical findings.
Indexed as
Identifiers
25550873PMC4270591W1466765220What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.