ArticleBeilstein journal of organic chemistry2014
A general metal-free approach for the stereoselective synthesis of C-glycals from unactivated alkynes.
Article in Beilstein journal of organic chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Electrochemical Ferrier rearrangement of glycals in flow.Communications chemistry · 2026Article
- Synergistic Gold-Silicon Catalysis: Unravelling Alkynyl Gold Reactivity and Application to the High-Performance C-Alkynylation of Glycals.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- TMSOTf mediated stereoselective synthesis of α-C-glycosides from unactivated aryl acetylenes.Glycoconjugate journal · 2017Article
- Gold-Catalyzed Vinyl Ether Hydroalkynylation: An Alternative Pathway for the Gold-Catalyzed Intermolecular Reaction of Alkenes and Alkynes.Organic letters · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
A novel metal-free strategy for a rapid and α-selctive C-alkynylation of glycals was developed. The reaction utilizes TMSOTf as a promoter to generate in situ trimethylsilylacetylene for C-alkynylation. Thanks to this methodology, we can access C-glycosides in a single step from a variety of acetylenes , i.e., arylacetylenes and most importantly aliphatic alkynes.
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Registered trials
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