Evidence map›Paper›PMID 25550314›Full record

ReviewAmerican journal of physiology. Lung cellular and molecular physiology2015

Working with nitric oxide and hydrogen sulfide in biological systems.

Shuai Yuan, Rakesh P Patel, Christopher G Kevil

Open access · greenAbstract readReview
In one paragraph

Review in American journal of physiology. Lung cellular and molecular physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 73 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The NOS/NO System in Renal Programming and Reprogramming.Antioxidants (Basel, Switzerland) · 2023
    Review
  5. Review
  6. Review
  7. Article
  8. Endogenous SORedox biology · 2021
    Article
  9. Article
  10. Reactive Sulfur Species: A New Redox Player in Cardiovascular Pathophysiology.Arteriosclerosis, thrombosis, and vascular biology · 2020
    Article
  11. Review
  12. Review
  13. Review
  14. Cystathionine γ-Lyase Modulates Flow-Dependent Vascular Remodeling.Arteriosclerosis, thrombosis, and vascular biology · 2018
    Article
  15. Article
  16. Article
  17. Review
  18. Phytochemical Analysis of Anti-Inflammatory and Antioxidant Effects ofOxidative medicine and cellular longevity · 2018
    Article
  19. Review
  20. Gasotransmitter Heterocellular Signaling.Antioxidants & redox signaling · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Shuai YuanDepartment of Pathology, Louisiana State University Health Sciences Center, Shreveport, Louisiana; and.
Rakesh P PatelDepartment of Pathology, University of Alabama at Birmingham, Birmingham, Alabama rakeshp@uab.edu.
Christopher G KevilDepartment of Pathology, Louisiana State University Health Sciences Center, Shreveport, Louisiana; and.
Louisiana State University Health Sciences Center Shreveport · USUniversity of Alabama at Birmingham · US

Funding

Nitrite dependent protection against Cl2 gas toxicity_role of chlorinated lipidsU01ES023759 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI PATEL, RAKESH P. · 2013 to 2018
$3.9M
Hydrogen sulfide and vascular remodelingR01HL113303 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI KEVIL, CHRISTOPHER G · 2012 to 2016
$1.8M
NHLBI NIH HHS HL11331NHLBI NIH HHS R01 HL113303NIEHS NIH HHS 1U01ES023759NIEHS NIH HHS U01 ES023759
6 · The paper itself

Abstract

Nitric oxide (NO) and hydrogen sulfide (H2S) are gasotransmitter molecules important in numerous physiological and pathological processes. Although these molecules were first known as environmental toxicants, it is now evident that that they are intricately involved in diverse cellular functions with impact on numerous physiological and pathogenic processes. NO and H2S share some common characteristics but also have unique chemical properties that suggest potential complementary interactions between the two in affecting cellular biochemistry and metabolism. Central among these is the interactions between NO, H2S, and thiols that constitute new ways to regulate protein function, signaling, and cellular responses. In this review, we discuss fundamental biochemical principals, molecular functions, measurement methods, and the pathophysiological relevance of NO and H2S.

Indexed as

AnimalsHumansHydrogen SulfideLung DiseasesModels, BiologicalNitric OxideNitric Oxide DonorsNitritesHydrogen SulfideNitric OxideNitric Oxide DonorsNitritescardiovascularoxidationpulmonaryredoxthiol

Identifiers

PMID25550314
PMCPMC4346774
OpenAlexW2048594060

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.