Evidence map›Paper›PMID 25550221›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2015

Characteristics and intraoperative treatments associated with head and neck free tissue transfer complications and failures.

William R Hand, Julie R McSwain, Matthew D McEvoy, Bethany Wolf, Abdalrahman A Algendy, Matthew D Parks, John L Murray, Scott T Reeves

Open access · greenAbstract read
In one paragraph

Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. The use of artificial intelligence in reconstructive surgery for head and neck cancer: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Pooled it
  2. Association between blood transfusions and complications in head and neck reconstruction: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Pooled it
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  13. Blood Loss and Transfusion Rates in Microsurgical Head and Neck Reconstruction.Plastic and reconstructive surgery. Global open · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

William R HandMedical University of South Carolina, Charleston, South Carolina, USA handw@musc.edu.
Julie R McSwainMedical University of South Carolina, Charleston, South Carolina, USA.
Matthew D McEvoyMedical University of South Carolina, Charleston, South Carolina, USA.
Bethany WolfMedical University of South Carolina, Charleston, South Carolina, USA.
Abdalrahman A AlgendyMedical University of South Carolina, Charleston, South Carolina, USA.
Matthew D ParksMedical University of South Carolina, Charleston, South Carolina, USA.
John L MurrayMedical University of South Carolina, Charleston, South Carolina, USA.
Scott T ReevesMedical University of South Carolina, Charleston, South Carolina, USA.
Medical University of South Carolina · US

Funding

SOUTH CAROLINA CLINICAL & TRANSLATIONAL RESEARCH INSTITUTE (SCTR)UL1RR029882 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2009 to 2011
$10.1M
South Carolina Clinical & Translational Research Institute (SCTR)UL1TR000062 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2012 to 2014
$9.4M
NCATS NIH HHS UL1 TR000062NCATS NIH HHS UL1TR000062NCRR NIH HHS UL1 RR029882NCRR NIH HHS UL1RR029882
6 · The paper itself

Abstract

objectiveTo investigate the association between perioperative patient characteristics and treatment modalities (eg, vasopressor use and volume of fluid administration) with complications and failure rates in patients undergoing head and neck free tissue transfer (FTT). STUDY

designA retrospective review of medical records.

settingPerioperative hospitalization for head and neck FTT at 1 tertiary care medical center between January 1, 2009, and October 31, 2011. SUBJECTS AND

methodsConsecutive patients (N=235) who underwent head and neck FTT. Demographic, patient characteristic, and intraoperative data were extracted from medical records. Complication and failure rates within the first 30 days were collected

resultsIn a multivariate analysis controlling for age, sex, ethnicity, reason for receiving flap, and type and volume of fluid given, perioperative complication was significantly associated with surgical blood loss (P=.019; 95% confidence interval [CI], 1.01-1.16), while the rate of intraoperative fluid administration did not reach statistical significance (P=.06; 95% CI, 0.99-1.28). In a univariate analysis, FTT failure was significantly associated with reason for surgery (odds ratio, 5.40; P=.03; 95% CI, 1.69-17.3) and preoperative diagnosis of coronary artery disease (odds ratio, 3.60; P=.03; 95% CI, 1.16-11.2). Intraoperative vasopressor administration was not associated with either FTT complication or failure rate.

conclusionsFTT complications were associated with surgical blood loss but not the use of vasoactive drugs. For patients undergoing FTT, judicious monitoring of blood loss may help stratify the risk of complication and failure.

Indexed as

Free Tissue FlapsFemaleFollow-Up StudiesHead and Neck NeoplasmsHumansIncidenceIntraoperative CareMaleMiddle AgedOdds RatioPlastic Surgery ProceduresPostoperative ComplicationsRetrospective StudiesRisk FactorsSouth CarolinaTreatment Failureanesthesia managementhead and neck free tissue transferintraoperative blood lossintraoperative fluid managementintraoperative vasopressors

Identifiers

PMID25550221
PMCPMC4516157
OpenAlexW2064174405

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.