Evidence map›Paper›PMID 25550175›Full record

ArticleAnatolian journal of cardiology2015

Plasma urotensin II and neurokinin B levels in acute myocardial infarction and stable coronary artery disease.

Dursun Çayan Akkoyun, Aydın Akyüz, Şeref Alpsoy, Ahmet Gürel, Niyazi Güler, Hasan Değirmenci, Ümit Gürkan

Open access · hybridAbstract read
In one paragraph

Article in Anatolian journal of cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. The Protective Effect of Total Flavones fromEvidence-based complementary and alternative medicine : eCAM · 2018
    Article
  2. The value of urotensin II in patients with left-sided rheumatic valvular regurgitation.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Dursun Çayan AkkoyunDepartment of Cardiology, Faculty of Medicine, Namık Kemal University; Tekirdağ-Turkey. cayanakkoyun@gmail.com.
Aydın Akyüz
Şeref Alpsoy
Ahmet Gürel
Niyazi Güler
Hasan Değirmenci
Ümit Gürkan
Namık Kemal University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis aim of the study is to investigate whether there are possible plasma urotensin-II (U-II) and neurokinin B (NKB) level changes in patients with acute myocardial infarction (AMI) or not and plasma urotensin-II (U-II) and neurokinin B (NKB) level changes in patients with acute myocardial infarction (AMI) and stable coronary artery disease (CAD) and to evaluate whether there is any relationship between these changes and the pathogenesis of these diseases.

methodsThis is a prospective case-control study. Three groups were formed from randomly admitted patients with AMI, stable CAD, and controls. Biochemical parameters and U-II and NKB levels were measured. Patients with congestive heart failure, chronic hepatic and renal failure, severe cardiac valve disease, and severe pulmonary hypertension were excluded from the study. The normality of the data was evaluated using the Kolmogorov-Smirnov test. We compared the three groups with one-way ANOVA and Tukey test (Kruskal-Wallis test and Mann-Whitney U test).

resultsCompared with controls (n=31) and CAD patients (n=32), AMI patients (n=32) had lower U-II and NKB levels. In cases of stable CAD, U-II and NKB levels were similar. A positive correlation was found between U-II and NKB (r=0.720; p=0.000). U-II and NKB were poorly correlated with left ventricle ejection fraction but not with C-reactive protein.

conclusionWe found that U-II and NKB levels were lower in patients with AMİ in than those with CAD or the control group. According to our findings, the decreased U-II and NKB levels were related to complicated atherosclerotic events.

Indexed as

BiomarkersCase-Control StudiesCoronary Artery DiseaseFemaleHumansMaleMiddle AgedMyocardial InfarctionNeurokinin BProspective StudiesUltrasonographyUrotensinsBiomarkersNeurokinin Burotensin IIUrotensins

Identifiers

PMID25550175
PMCPMC5336863
OpenAlexW2074517532

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.