ArticleAnatolian journal of cardiology2015
The association between platelet/lymphocyte ratio and coronary artery disease severity.
Article in Anatolian journal of cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
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Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Predictive value of lymphocyte-associated inflammation index in post-stroke cognitive impairment: a systematic review and meta-analysis.Frontiers in neurology · 2024Pooled it
- Association of thrombocytopenia with deep vein thrombosis in patients with acute exacerbations of chronic obstructive pulmonary disease: A retrospective study.Experimental and therapeutic medicine · 2026Article
- HearteXplain: explainable prediction of acute heart failure and identification of hematologic biomarkers using EBMs and Morris sensitivity analysis.Scientific reports · 2025Article
- Neutrophil Percentage-to-Albumin Ratio and Coronary Collaterals: A True Predictor or an Overstated Association?Anatolian journal of cardiology · 2025Article
- Development and Validation of an Explainable Prediction Model to Assess the Risk of Coronary Artery Disease in Young and Middle-Aged Individuals.Reviews in cardiovascular medicine · 2025Article
- Correlation and Risk Assessment of Inflammation-Based Parameters on Cardiovascular Parameters and Clinical Events in Giant Cell Arteritis: A Retrospective Study.International journal of molecular sciences · 2025Article
- Neutrophil Percentage-to-Albumin Ratio as a Predictor of Collateral Circulation in Chronic Total Occlusion.Anatolian journal of cardiology · 2025Article
- Predictive Value of the Naples Prognostic Score for One-Year Mortality in NSTEMI Patients Undergoing Selective PCI.Diagnostics (Basel, Switzerland) · 2025Article
- The Prognostic Value of Inflammatory Indices in Acute Pulmonary Embolism.Diagnostics (Basel, Switzerland) · 2025Article
- Article
- Association between advanced lung cancer inflammation index and atherosclerosis cardiovascular disease in U.S. adults: a population-based investigation.Frontiers in nutrition · 2025Article
- Prognosis impact of multiple novel lymphocyte-based inflammatory indices in patients with initially diagnosed coronary artery disease.Immunity, inflammation and disease · 2024Article
- Residual Cardiovascular Risk: Role of Remnants Cholesterol, Monocyte/HDL Ratio and Lipoprotein Ratios on Personalized Cardiovascular Prevention.Journal of personalized medicine · 2024Review
- The utility of the systemic immune inflammation and systemic inflammation response indices in suspected intermediate-risk pulmonary embolism.Croatian medical journal · 2024Article
- Exploring the Correlation between Systemic Inflammatory Markers and Carotid Atherosclerosis Indices in Middle-Aged Adults: A Cross-Sectional Study.Journal of cardiovascular development and disease · 2024Article
- The Relationship between the Systemic Immune-Inflammation Index and Ischemia with Non-Obstructive Coronary Arteries in Patients Undergoing Coronary Angiography.Arquivos brasileiros de cardiologia · 2024Article
- The early predictive value of platelet-to-lymphocyte ratio to hemorrhagic transformation of young acute ischemic stroke.Asian biomedicine : research, reviews and news · 2023Article
- Predictive value of the systemic immune inflammatory index in cardiac syndrome x.BMC cardiovascular disorders · 2023Article
- Towards a biomarker for acute arterial thrombosis using complete blood count and white blood cell differential parameters in mice.Scientific reports · 2023Article
- Relationship between Glucose-6-Phosphate Dehydrogenase Deficiency, X-Chromosome Inactivation and Inflammatory Markers.Antioxidants (Basel, Switzerland) · 2023Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIn this study, we aimed to explore the association between platelet-to-lymphocyte ratio (PLR) and the severity of atherosclerosis in coronary artery disease (CAD).
methodsClinical and laboratory data of 388 patients who underwent coronary angiography were evaluated retrospectively. Gensini score, which indicates the severity of atherosclerosis, was calculated for all of the patients. Patients with CAD were categorized as mild and severe atherosclerosis, according to their Gensini score. Eighty patients with normal coronary arteries formed the control group. Mean PLR values of the three study groups were compared. Also, PLR value was tested for whether it showed a positive correlation with Gensini score.
resultsThe mean PLR of the severe atherosclerosis group was significantly higher than that of the mild atherosclerosis and controls groups (p<0.001). Also, PLR was positively correlated with Gensini score in CAD patients. A cut-off value of 111 for PLR predicted severe atherosclerosis with 61% sensitivity and 59% specificity. Pre-procedural PLR level was found to be independently associated with Gensini score, together with WBC, age, and low HDL level, in the multivariate analysis.
conclusionOur study suggests that high PLR appears to be additive to conventional risk factors and commonly used biomarkers in predicting severe atherosclerosis.
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