ArticleVirus research2015
New insights on the role of paired membrane structures in coronavirus replication.
Article in Virus research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 22 citations in OpenAlex.
- The DMV pore-forming TM2-Y region of SARS-CoV-2 nsp3 exhibits structural conservation beyond the coronavirus family.Journal of virology · 2026Article
- Hepatitis Viruses Control Host Immune Responses by Modifying the Exosomal Biogenesis Pathway and Cargo.International journal of molecular sciences · 2022Review
- Alterations of Lipid Profile in COVID-19: A Narrative Review.Current problems in cardiology · 2022Review
- A Defective Viral Particle Approach to COVID-19.Cells · 2022Review
- Dissecting lipid metabolism alterations in SARS-CoV-2.Progress in lipid research · 2021Review
- Evidences for lipid involvement in SARS-CoV-2 cytopathogenesis.Cell death & disease · 2021Article
- Advances in developing small molecule SARS 3CLTetrahedron · 2021Review
- Understanding the complexities of SARS-CoV2 infection and its immunology: A road to immune-based therapeutics.International immunopharmacology · 2020Review
- Extracellular Vesicles in Viral Infections: Two Sides of the Same Coin?Frontiers in cellular and infection microbiology · 2020Review
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- Inhibition of Cytosolic Phospholipase AJournal of virology · 2018Article
- Interaction of the innate immune system with positive-strand RNA virus replication organelles.Cytokine & growth factor reviews · 2017Article
- Bioinformatics and functional analyses of coronavirus nonstructural proteins involved in the formation of replicative organelles.Antiviral research · 2016Review
- Extensive coronavirus-induced membrane rearrangements are not a determinant of pathogenicity.Scientific reports · 2016Article
- High-Resolution Analysis of Coronavirus Gene Expression by RNA Sequencing and Ribosome Profiling.PLoS pathogens · 2016Article
- The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing.Advances in virus research · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The replication of coronaviruses, as in other positive-strand RNA viruses, is closely tied to the formation of membrane-bound replicative organelles inside infected cells. The proteins responsible for rearranging cellular membranes to form the organelles are conserved not just among the Coronaviridae family members, but across the order Nidovirales. Taken together, these observations suggest that the coronavirus replicative organelle plays an important role in viral replication, perhaps facilitating the production or protection of viral RNA. However, the exact nature of this role, and the specific contexts under which it is important have not been fully elucidated. Here, we collect and interpret the recent experimental evidence about the role and importance of membrane-bound organelles in coronavirus replication.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.