SynthesisBehavioural brain research2015
A systems approach to stress, stressors and resilience in humans.
Synthesis in Behavioural brain research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
84 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- An Overview of Stress Analysis Based on Physiological Signals: Systematic Review of Open Datasets and Current Trends.Sensors (Basel, Switzerland) · 2025Pooled it
- Social class and the risk of dementia: A systematic review and meta-analysis of the prospective longitudinal studies.Scandinavian journal of public health · 2023Pooled it
- Resilience Intervention for Parents of Children with Autism: Findings from a Randomized Controlled Trial of the AMOR Method.Journal of autism and developmental disorders · 2022Trial
- How does yoga reduce stress? A clinical trial testing psychological mechanisms.Stress and health : journal of the International Society for the Investigation of Stress · 2021Trial
- Psychosocial factors associated with poor outcomes after amputation for complex regional pain syndrome type-I.PloS one · 2019Trial
- Aroma Effects on Physiologic and Cognitive Function Following Acute Stress: A Mechanism Investigation.Journal of alternative and complementary medicine (New York, N.Y.) · 2016Trial
- Mechanistic Pathways of Mindfulness Meditation in Combat Veterans With Posttraumatic Stress Disorder.Journal of clinical psychology · 2016Trial
- Internet-based Mindfulness Meditation for Cognition and Mood in Older Adults: A Pilot Study.Alternative therapies in health and medicineTrial
- Toward targeted mental health support: the (in)congruence effect of resilience and social support among casino employees in Macau.BMC public health · 2026Article
- Cognitive biotypes identified through ECG-derived workload and behavioral accuracy.Scientific reports · 2026Article
- Silenced, stigmatised and struggling: early childbearing, minority stress and mental distress among pregnant and parenting adolescent girls in an urban informal settlement in Kenya - an explanatory qualitative study.BMJ public health · 2026Article
- Allostatic load and uterine fibroids: role in pathogenesis and racial disparities.Uterine research · 2026Review
- Estradiol and non-REM sleep attenuate physiological and emotional responses to social-evaluative stress in healthy women.BMC medicine · 2025Article
- Potential Mechanisms of Influence Between Spiritual Practices and Cognitive Health: A Systematic Review and Conceptual Model.Brain sciences · 2025Review
- Inferring Mental States via Linear and Non-Linear Body Movement Dynamics: A Pilot Study.Sensors (Basel, Switzerland) · 2025Article
- A new wide-scope, multi-biomarker wastewater-based epidemiology analytical method to monitor the health and well-being of inhabitants at a metropolitan scale.Analytical and bioanalytical chemistry · 2025Article
- Facial Temperature Responses to Ostracism in Women: Exploring Nasal Thermal Signatures of Different Coping Behaviors.Psychophysiology · 2025Article
- Patterns of Respiration Rate Reactivity in Response to a Cognitive Stressor Associate With Self-Reported Mental Health Outcomes.Psychological reports · 2025Article
- "Methyl jasmonate: bridging plant defense mechanisms and human therapeutics".Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Current Strategies and Future Directions of Wearable Biosensors for Measuring Stress Biochemical Markers for Neuropsychiatric Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
24 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The paper focuses on the biology of stress and resilience and their biomarkers in humans from the system science perspective. A stressor pushes the physiological system away from its baseline state toward a lower utility state. The physiological system may return toward the original state in one attractor basin but may be shifted to a state in another, lower utility attractor basin. While some physiological changes induced by stressors may benefit health, there is often a chronic wear and tear cost due to implementing changes to enable the return of the system to its baseline state and maintain itself in the high utility baseline attractor basin following repeated perturbations. This cost, also called allostatic load, is the utility reduction associated with both a change in state and with alterations in the attractor basin that affect system responses following future perturbations. This added cost can increase the time course of the return to baseline or the likelihood of moving into a different attractor basin following a perturbation. Opposite to this is the system's resilience which influences its ability to return to the high utility attractor basin following a perturbation by increasing the likelihood and/or speed of returning to the baseline state following a stressor. This review paper is a qualitative systematic review; it covers areas most relevant for moving the stress and resilience field forward from a more quantitative and neuroscientific perspective.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.