Evidence map›Paper›PMID 25548989›Full record

ArticlePsychosomatic medicine2015

Racial and ethnic differences in diurnal cortisol rhythms: are they consistent over time?

Amy S DeSantis, Emma K Adam, Louise C Hawkley, Brigitte M Kudielka, John T Cacioppo

Abstract read
PubMed Publisher
In one paragraph

Article in Psychosomatic medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amy S DeSantisFrom the Department of Social Sciences and Humanities (A.S.D.), Indian Institute of Technology-Gandhinagar, Ahmedabad, Gujarat, India; Program on Human Development and Social Policy (E.K.A.), Cells to Society: Center for Social Epidemiology and Health, Northwestern University, Evanston, Illinois; Academic Research Centers (L.C.H.), NORC, University of Chicago, Chicago, Illinois; Department of Medical Psychology and Psychological Diagnostics (B.M.K.), University of Regensburg, Regensburg, Germany; Department of Psychology and Center for Cognitive and Social Neuroscience (J.T.C.), University of Chicago, Chicago, Illinois.
Emma K Adam
Louise C Hawkley
Brigitte M Kudielka
John T Cacioppo
Northwestern University · US

Funding

NIA NIH HHS P01 AG1891
6 · The paper itself

Abstract

backgroundPrior research indicates that blacks and Hispanics/Latinos have flatter diurnal cortisol declines across the day, a profile associated with poorer health. The stability of racial and ethnic differences in cortisol levels over time is not well understood, and additional research is needed to establish racial and ethnic differences in psychosocial stress levels as related to changes in cortisol levels.

methodsWith data from a community-based study of 152 adults (mean age = 58 years; 53% women; 34% black, 26% Hispanic/Latino), we examined the magnitude of racial and ethnic differences over a 5-year period. Salivary cortisol samples were obtained 3 times per day for 3 days in Years 1, 3, 4, and 5. Life events and chronic stress were assessed by questionnaires in which participants reported on whether they had experienced specific types of events or stress within the past year. Depressive symptoms scales (Center for Epidemiologic Studies of Depression Scale) were also administered annually. Daily cortisol slopes were calculated by subtracting wakeup cortisol from bedtime levels and dividing by hours awake.

resultsIncreases in psychosocial stress were associated with flatter cortisol slopes among blacks (β = 0.010) and Hispanics/Latinos (β = 0.014), although including cardiovascular disease risk factors attenuates associations in blacks (β = 0.007; p = .125). Higher income predicts a steepening of cortisol rhythms across the study (β = -0.003; p = .019).

conclusionsRacial and ethnic differences in diurnal cortisol rhythms are stable over time. However, the magnitude of changes in cortisol levels associated with chronic stress levels may vary by racial and ethnic subgroups.

Indexed as

Circadian RhythmEthnicityAgedBlack or African AmericanDepressionFemaleHispanic or LatinoHumansHydrocortisoneHypothalamo-Hypophyseal SystemIncomeLongitudinal StudiesMaleMiddle AgedPituitary-Adrenal SystemRisk FactorsHydrocortisone

Identifiers

PMID25548989
OpenAlexW2333183111

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.