Evidence map›Paper›PMID 25548803›Full record

ReviewCellular and molecular life sciences : CMLS2015

Interactions between host factors and the skin microbiome.

Adam SanMiguel, Elizabeth A Grice

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Nationality and body location alter human skin microbiome.Applied microbiology and biotechnology · 2021
    Pooled it
  2. Article
  3. Article
  4. Microbiology spectrum · 2026
    Article
  5. Article
  6. Article
  7. Antibacterial and Antibiofilm Properties of Postbiotics Derived fromInternational journal of molecular sciences · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Biofilm · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Effects of exogenous elevation of corticosterone on immunity and the skin microbiome of eastern newts (Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adam SanMiguelDepartment of Dermatology, University of Pennsylvania, Perelman School of Medicine, 421 Curie Blvd, 1007 Biomedical Research Building II/III, Philadelphia, PA, 19104, USA.
Elizabeth A Grice

Funding

The Microbiome of Impaired Wound HealingR00AR060873 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI GRICE, ELIZABETH ANNE · 2012 to 2014
$730k
NIAMS NIH HHS R00 AR060873
6 · The paper itself

Abstract

The skin is colonized by an assemblage of microorganisms which, for the most part, peacefully coexist with their hosts. In some cases, these communities also provide vital functions to cutaneous health through the modulation of host factors. Recent studies have illuminated the role of anatomical skin site, gender, age, and the immune system in shaping the cutaneous ecosystem. Alterations to microbial communities have also been associated with, and likely contribute to, a number of cutaneous disorders. This review focuses on the host factors that shape and maintain skin microbial communities, and the reciprocal role of microbes in modulating skin immunity. A greater understanding of these interactions is critical to elucidating the forces that shape cutaneous populations and their contributions to skin homeostasis. This knowledge can also inform the tendency of perturbations to predispose and/or bring about certain skin disorders.

Indexed as

MicrobiotaAge FactorsCD8-Positive T-LymphocytesHumansImmune SystemSex FactorsSkinSkin Diseases

Identifiers

PMID25548803
PMCPMC4376244

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.