Evidence map›Paper›PMID 25548569›Full record

ReviewInternational journal of otolaryngology2014

Nasal involvement in obstructive sleep apnea syndrome.

Daniel de Sousa Michels, Amanda da Mota Silveira Rodrigues, Márcio Nakanishi, André Luiz Lopes Sampaio, Alessandra Ramos Venosa

Abstract readReview
In one paragraph

Review in International journal of otolaryngology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Variability in Physical Exam Documentation for Obstructive Sleep Apnea.Laryngoscope investigative otolaryngology · 2026
    Article
  2. Article
  3. Breathing changes following mini-implant-supported maxillary skeletal expander treatment in late adolescent or adult patients : Assessment of objective and subjective functional breathing changes.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2025
    Article
  4. Prevalence of Obstructive Sleep Apnoea in patients with primary nasal and nasopharyngeal pathologies.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  5. A Systematic Review of Risk factors for Sleep Apnea.Preventive medicine reports · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Pressure Requirements With a Nasal Versus Oronasal Mask During a PAP Titration Study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019
    Article
  11. The complex pathophysiology of allergic rhinitis: scientific rationale for the development of an alternative treatment option.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2019
    Review
  12. Article
  13. Does nasal congestion have a role in decreased resistance to regular CPAP usage?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017
    Article
  14. A comparative study on oxidative stress role in nasal breathing impairment and obstructive sleep apnoea syndrome.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2016
    Article
  15. Article
  16. Obstructive sleep apnoea syndrome and its management.Therapeutic advances in chronic disease · 2015
    Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel de Sousa MichelsDepartment of Otorhinolaryngology and Head and Neck Surgery, Brasília University Hospital, HUB, SGAN 605, Avenida L2 Norte, 70830-200 Brasília, DF, Brazil.
Amanda da Mota Silveira RodriguesUniversidade de Brasília (UnB), Campus Universitário Darcy Ribeiro, 70910-900 Brasília, DF, Brazil.
Márcio NakanishiDepartment of Otorhinolaryngology and Head and Neck Surgery, Brasília University Hospital, HUB, SGAN 605, Avenida L2 Norte, 70830-200 Brasília, DF, Brazil.
André Luiz Lopes SampaioDepartment of Otorhinolaryngology and Head and Neck Surgery, Brasília University Hospital, HUB, SGAN 605, Avenida L2 Norte, 70830-200 Brasília, DF, Brazil ; Universidade de Brasília (UnB), Campus Universitário Darcy Ribeiro, 70910-900 Brasília, DF, Brazil.
Alessandra Ramos VenosaDepartment of Otorhinolaryngology and Head and Neck Surgery, Brasília University Hospital, HUB, SGAN 605, Avenida L2 Norte, 70830-200 Brasília, DF, Brazil ; Universidade de Brasília (UnB), Campus Universitário Darcy Ribeiro, 70910-900 Brasília, DF, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous studies have reported an association between nasal obstruction and obstructive sleep apnea syndrome (OSAS), but the precise nature of this relationship remains to be clarified. This paper aimed to summarize data and theories on the role of the nose in the pathophysiology of sleep apnea as well as to discuss the benefits of surgical and medical nasal treatments. A number of pathophysiological mechanisms can potentially explain the role of nasal pathology in OSAS. These include the Starling resistor model, the unstable oral airway, the nasal ventilatory reflex, and the role of nitric oxide (NO). Pharmacological treatment presents some beneficial effects on the frequency of respiratory events and sleep architecture. Nonetheless, objective data assessing snoring and daytime sleepiness are still necessary. Nasal surgery can improve the quality of life and snoring in a select group of patients with mild OSAS and septal deviation but is not an effective treatment for OSA as such. Despite the conflicting results in the literature, it is important that patients who are not perfectly adapted to CPAP are evaluated in detail, in order to identify whether there are obstructive factors that could be surgically corrected.

Identifiers

PMID25548569
PMCPMC4273597

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.