ReviewInternational journal of endocrinology2014
MicroRNAs in Human Pituitary Adenomas.
Review in International journal of endocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 172 citations in OpenAlex.
- Gene expression in prolactinomas: a systematic review.Pituitary · 2016Pooled it
- Liquid Biopsy in Pituitary Neuroendocrine Tumors-Potential Biomarkers for Diagnosis, Prognosis, and Therapy.International journal of molecular sciences · 2025Review
- Review
- BMPMDA: Prediction of MiRNA-Disease Associations Using a Space Projection Model Based on Block Matrix.Interdisciplinary sciences, computational life sciences · 2023Article
- Aggressive nonfunctioning pituitary neuroendocrine tumors.Brain tumor pathology · 2022Review
- Marine Anthraquinones: Pharmacological and Toxicological Issues.Marine drugs · 2021Review
- Article
- Limitations of high throughput methods for miRNA expression profiles in non-functioning pituitary adenomas.Pathology oncology research : POR · 2019Article
- Identification and characterization of microRNAs in the pituitary of pubescent goats.Reproductive biology and endocrinology : RB&E · 2018Article
- Increased miR-338-3p expression correlates with invasiveness of GH-producing pituitary adenomas.Endocrine · 2017Article
- MicroRNA-200b inhibits pituitary tumor cell proliferation and invasion by targeting PKCα.Experimental and therapeutic medicine · 2017Article
- Systematic Investigation of Expression of G2/M Transition Genes Reveals CDC25 Alteration in Nonfunctioning Pituitary Adenomas.Pathology oncology research : POR · 2017Article
- MicroRNA-106b promotes pituitary tumor cell proliferation and invasion through PI3K/AKT signaling pathway by targeting PTEN.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016Article
- Pituitary Adenoma and the Chemokine Network: A Systemic View.Frontiers in endocrinology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs (miRNAs) are a class of recently identified noncoding RNAs that regulate gene expression at posttranscriptional level. Due to the large number of genes regulated by miRNAs, miRNAs play important roles in many cellular processes. Emerging evidence indicates that miRNAs are dysregulated in pituitary adenomas, a class of intracranial neoplasms which account for 10-15% of diagnosed brain tumors. Deregulated miRNAs and their targets contribute to pituitary adenomas progression and are associated with cell cycle control, apoptosis, invasion, and pharmacological treatment of pituitary adenomas. To provide an overview of miRNAs dysregulation and functions of these miRNAs in pituitary adenoma progression, we summarize the deregulated miRNAs and their targets to shed more light on their potential as therapeutic targets and novel biomarkers.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.