Evidence map›Paper›PMID 25548319›Full record

Observational studyThe British journal of general practice : the journal of the Royal College of General Practitioners2015

Predicting blood pressure outcomes using single-item physician-administered measures: a retrospective pooled analysis of observational studies in Belgium.

Lorenzo Villa, Diana Sun, Kris Denhaerynck, Stefaan Vancayzeele, Heidi Brié, Christine Hermans, Ann Aerts, Michael Levengood, Karen MacDonald, Ivo Abraham

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in The British journal of general practice : the journal of the Royal College of General Practitioners, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Lorenzo VillaFaculty of Pharmacy, University of Concepción, Concepción, Chile.
Diana SunCenter for Health Outcomes & PharmacoEconomic Research, College of Pharmacy, The University of Arizona, Tucson, AZ, US.
Kris DenhaerynckMatrix45, Basel, Switzerland.
Stefaan VancayzeeleNovartis Pharma, Vilvoorde, Belgium.
Heidi BriéNovartis Pharma, Vilvoorde, Belgium.
Christine HermansNovartis Pharma, Vilvoorde, Belgium.
Ann AertsNovartis Pharma, Vilvoorde, Belgium.
Michael LevengoodCenter for Health Outcomes and PharmacoEconomic Research, The University of Arizona, Tucson, AZ, US.
Karen MacDonaldMatrix45, Tucson, AZ, US.
Ivo AbrahamCenter for Health Outcomes & PharmacoEconomic Research; Department of Pharmacy Practice & Science, College of Pharmacy; Department of Family and Community Medicine, College of Medicine, The University of Arizona, Tucson, AZ, US.
Novartis (Belgium) · BEPharmacoeconomics and Health Outcomes Research Iberia (Spain) · ESUniversity of Concepción · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatient adherence is often not monitored because existing methods of evaluating adherence are either burdensome or do not accurately predict treatment outcomes.

aimTo examine whether two simple, single-item physician-administered measures of patient adherence to antihypertensive medication are predictive of blood pressure outcomes. DESIGN AND

settingRetrospective database analysis of patients with hypertension treated in Belgian primary care.

methodUsing pooled data from five observational studies, a sample was identified of 9725 patients who were assessed using two single-item physician-administered measures of adherence to antihypertensive medication: the first item of the Basel Assessment of Adherence Scale (BAAS) and the Visual Analogue Scale (VAS). These two assessment tools were administered by GPs during regular appointments with patients. Systolic blood pressure (SBP), diastolic blood pressure (DBP), and combined SBP/DBP were measured at baseline and at 90 days.

resultsBAAS-identified adherent patients achieved lower mean SBP and DBP compared with non-adherent patients at 90 days (P<0.001), and had odds ratios of achieving blood pressure control of 0.66 (95% confidence intervals (CI) = 0.61 to 0.73, P<0.001) for SBP, 0.69 (95% CI = 0.62 to 0.76, P<0.001) for DBP, and 0.65 (95% CI = 0.59 to 0.72, P<0.001) for combined SBP/DBP. For VAS-identified adherent patients, the odds ratios of achieving blood pressure control were 0.93 (95% CI = 0.86 to 1.00, P<0.001) for SBP, 0.79 (95% CI = 0.73 to 0.85, P<0.001) for DBP, and 0.91 (95% CI = 0.84 to 0.99, P<0.001) for combined SBP/DBP.

conclusionsThe first item of the BAAS and the VAS are independent predictors of blood pressure control. These methods can be integrated seamlessly into routine clinical practice by allowing GPs to quickly evaluate a patient's adherence and tailor treatment recommendations accordingly.

Indexed as

Cost of IllnessDrug MonitoringHypertensionVisual Analog ScaleAgedAntihypertensive AgentsBelgiumBlood PressureBlood Pressure DeterminationFemaleHumansMaleMiddle AgedOutcome Assessment, Health CarePrimary Health CarePrognosisAntihypertensive Agentshypertensionmedication adherencepatient adherenceprimary health care

Identifiers

PMID25548319
PMCPMC4276010
OpenAlexW1984467003

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.