ArticlePhilosophical transactions. Series A, Mathematical, physical, and engineering sciences2015
Assessing levels of consciousness with symbolic analysis.
Article in Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Characteristics of electroencephalographic changes induced by different hypnotics in elderly patients: a narrative review.Korean journal of anesthesiology · 2026Review
- Wakefulness can be distinguished from general anesthesia and sleep in flies using a massive library of univariate time series analyses.PLoS biology · 2025Article
- Assessing consciousness in patients with locked-in syndrome using their EEG.Frontiers in neuroscience · 2025Article
- Capturing spontaneous interactivity: a multi-measure approach to analyzing the dynamics of interpersonal coordination in dance improvisation.Frontiers in psychology · 2024Article
- Assessing consciousness in patients with disorders of consciousness using soft-clustering.Brain informatics · 2023Article
- Application of Soft-Clustering to Assess Consciousness in a CLIS Patient.Brain sciences · 2022Article
- Selective corticocortical connectivity suppression during propofol-induced anesthesia in healthy volunteers.Cognitive neurodynamics · 2022Article
- A review of methods used to kill laboratory rodents: issues and opportunities.Laboratory animals · 2022Review
- Theoretical Models of Consciousness: A Scoping Review.Brain sciences · 2021Article
- Interpersonal Physiological Synchrony for Detecting Moments of Connection in Persons With Dementia: A Pilot Study.Frontiers in psychology · 2021Article
- Motor-system dynamics during naturalistic reading of action narratives in first and second language.NeuroImage · 2020Article
- Development of a point of care system for automated coma prognosis: a prospective cohort study protocol.BMJ open · 2019Observational
- Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery.Trends in pharmacological sciences · 2019Review
- Role of Network Science in the Study of Anesthetic State Transitions.Anesthesiology · 2018Review
- Adrenergic Blockade Bi-directionally and Asymmetrically Alters Functional Brain-Heart Communication and Prolongs Electrical Activities of the Brain and Heart during Asphyxic Cardiac Arrest.Frontiers in physiology · 2018Article
- Functional and Topological Conditions for Explosive Synchronization Develop in Human Brain Networks with the Onset of Anesthetic-Induced Unconsciousness.Frontiers in computational neuroscience · 2016Article
- Enhancing dynamical signatures of complex systems through symbolic computation.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2015Article
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3 authors.
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Abstract
'Covert consciousness' is a state in which consciousness is present without the capacity for behavioural response, and it can occur in patients with intraoperative awareness or unresponsive wakefulness syndrome. To detect and prevent this undesirable state, it is critical to develop a reliable neurobiological assessment of an individual's level of consciousness that is independent of behaviour. One such approach that shows potential is measuring surrogates of cortical communication in the brain using electroencephalography (EEG). EEG is practicable in clinical application, but involves many fundamental signal processing problems, including signal-to-noise ratio and high dimensional complexity. Symbolic analysis of EEG can mitigate these problems, improving the measurement of brain connectivity and the ability to successfully assess levels of consciousness. In this article, we review the problem of covert consciousness, basic neurobiological principles of consciousness, current methods of measuring brain connectivity and the advantages of symbolic processing, with a focus on symbolic transfer entropy (STE). Finally, we discuss recent advances and clinical applications of STE and other symbolic analyses to assess levels of consciousness.
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