ArticlePloS one2014
Incidence of otitis media in a contemporary Danish National Birth Cohort.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 82 citations in OpenAlex.
- Trends in Tympanostomy Tube Insertion Among Children Aged 0-12 Years: A Register-Based Cohort Study in Denmark (2003-2023).Clinical epidemiology · 2026Article
- Bacterial Acute Otitis Media Complicated with Otorrhea in a Children's Hospital in the Era of Pneumococcal Conjugate Vaccines.Pathogens (Basel, Switzerland) · 2025Article
- Article
- Risk Factors for Chronic and Recurrent Otitis Media in Children: A Review Article.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Cohort profile: Born in Wales-a birth cohort with maternity, parental and child data linkage for life course research in Wales, UK.BMJ open · 2024Article
- Healthcare resource utilization and cost of pneumococcal disease in children in Germany, 2014-2019: a retrospective cohort study.Pneumonia (Nathan Qld.) · 2023Article
- Association Between Social Disadvantage and Otitis Media Treatment in US Children With Commercial Insurance.JAMA otolaryngology-- head & neck surgery · 2022Article
- The Impact of the COVID-19 Pandemic on Otitis Media.Viruses · 2022Review
- Association between maternal insecticide use and otitis media in one-year-old children in the Japan Environment and Children's Study.Scientific reports · 2022Article
- Postoperative results of ventilation tube insertion: a retrospective multicenter study for suggestion of grading system of otitis media with effusion.BMC pediatrics · 2021Article
- Identifying distinct trajectories of acute otitis media in children: A prospective cohort study.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2021Article
- Prescription of antibiotics to children with acute otitis media in Danish general practice.BMC family practice · 2020Article
- Risk Factors for Otitis Media in Children Referred to Abuzar Hospital in Ahvaz: A Case-Control Study.Cureus · 2020Article
- Early-life programming of pain sensation? Spinal pain in pre-adolescents with pain experience in early life.European journal of pediatrics · 2019Article
- Middle ear abnormalities at age 5 years in relation with early onset otitis media and number of episodes, in the Inuit population of Nunavik, Quebec, Canada.International journal of circumpolar health · 2019Article
- Treatment of Streptococcus pneumoniae otitis media in a chinchilla model by transtympanic delivery of antibiotics.JCI insight · 2018Article
- Hearing loss in children with Fabry disease.Journal of inherited metabolic disease · 2017Article
- The Effect of Breastfeeding on Childhood Otitis Media.Current allergy and asthma reports · 2017Review
- Prevalence of Middle Ear Infections and Associated Risk Factors in Children under 5 Years in Gasabo District of Kigali City, Rwanda.International journal of pediatrics · 2017Article
- Knowledge and care seeking practices for ear infections among parents of under five children in Kigali, Rwanda: a cross-sectional study.BMC ear, nose, and throat disorders · 2017Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesIn recent years welfare in Denmark has increased which might be expected to reduce otitis media (OM) incidence. We examined the age-specific incidence of OM in a nation-wide cohort of children aged 0-7 years born in 1996-2003 (Danish National Birth Cohort, DNBC). Only selection was ability to understand and speak Danish.
methodsInformation of OM and ventilation tubes (VT) was collected through three maternal interviews at 6-month, 18-month and 7-years of age and based on this age-specific and cumulative incidence of OM was calculated. As different numbers of the total population answered the different interviews, the calculations are done with different denominators. The information in DNBC was validated against two population based registries containing information of VT insertions.
resultsCumulative incidence of OM at 7 years was 60.6% (31,982/52,755). For children with OM, 16.2% (7143/44194) had their first OM episodes between 0-6 months of age, 44.3% (19579/44194) between 7-18 months, and 39.5% (17472/44194) between 19 months and 7 years. Four or more OM episodes before 7 years were reported by 39.5% (12620/31982) and by 64.0% (2482/3881) of those who had their OM debut between 0-6 months; by 48.2% (4998/10378) with debut between 7-18 months; and by 28.7% (4996/17344) with debut between 19 months and 7 years. These figures are essentially unchanged from earlier figures from Denmark. VT insertion at least once was reported by 26,1% in the 7-year interview. Assuming recordings in the Danish National Patient Registry to be gold standard, maternal self-reportings in DNBC of insertion of VT showed high sensitivity (96.4%), specificity (98.2%), and positive (94.8%) and negative predictive values (98.8%).
conclusionOM affects nearly 2/3 of preschool children in Denmark despite reduction in known OM risk factors.
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