Trial reportEarly human development2015
A randomised trial of continuous skin-to-skin contact after preterm birth and the effects on salivary cortisol, parental stress, depression, and breastfeeding.
Trial report in Early human development, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 13 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
81 citing papers in PubMed, 13 syntheses or guidelines pooled it, 245 citations in OpenAlex.
- Impact of kangaroo mother care on maternal postpartum depression: a systematic review and meta-analysis of controlled trials.Pediatric research · 2026Pooled it
- Assessment of cortisol as a neonatal pain biomarker in the application of non-pharmacological analgesia therapies: systematic review and meta-analysis.BMC pediatrics · 2025Pooled it
- The role of paternal support in breastfeeding outcomes: a meta-analytic review.International breastfeeding journal · 2024Pooled it
- Efficacy of home phototherapy versus inpatient phototherapy for neonatal hyperbilirubinemia: a systematic review and meta-analysis.Italian journal of pediatrics · 2024Pooled it
- Effect of tactile and/or kinesthetic stimulation therapy of preterm infants on their parents' anxiety and depressive symptoms: A systematic review.BMC psychology · 2024Pooled it
- Kangaroo mother care for preterm or low birth weight infants: a systematic review and meta-analysis.BMJ global health · 2023Pooled it
- Effects of kangaroo mother care on maternal and paternal health: systematic review and meta-analysis.Bulletin of the World Health Organization · 2023Pooled it
- Pooled it
- Attachment- and Relationship-Based Interventions during NICU Hospitalization for Families with Preterm/Low-Birth Weight Infants: A Systematic Review of RCT Data.International journal of environmental research and public health · 2022Pooled it
- Systematic review shows the benefits of involving the fathers of preterm infants in early interventions in neonatal intensive care units.Acta paediatrica (Oslo, Norway : 1992) · 2021Pooled it
- Parent-Infant Skin-to-Skin Contact and Stress Regulation: A Systematic Review of the Literature.International journal of environmental research and public health · 2021Pooled it
- Early skin-to-skin contact for mothers and their healthy newborn infants.The Cochrane database of systematic reviews · 2016Pooled it
- Kangaroo mother care to reduce morbidity and mortality in low birthweight infants.The Cochrane database of systematic reviews · 2016Pooled it
- Trial
- Effects of Kangaroo care during retinopathy screening examination: a randomised clinical trial.BMJ paediatrics open · 2026Trial
- Effects of home-based integrated sensory stimulation program to preterm infants on parents' depression and anxiety: a randomized controlled trial.Global health action · 2025Trial
- Skin-to-Skin Contact at Birth for Very Preterm Infants and Mother-Infant Interaction Quality at 4 Months: A Secondary Analysis of the IPISTOSS Randomized Clinical Trial.JAMA network open · 2023Trial
- Does immediate skin-to-skin contact at caesarean sections promote uterine contraction and recovery of the maternal blood haemoglobin levels? A randomized clinical trial.Nursing open · 2023Trial
- Effects of skin-to-skin contact on full-term infants' stress reactivity and quality of mother-infant interactions.Developmental psychobiology · 2022Trial
- Randomized clinical trial of the effect of the onset time of skin-to-skin contact at birth, immediate compared to early, on the duration of breastfeeding in full term newborns.International breastfeeding journal · 2021Trial
21 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate the effects of almost continuous skin-to-skin contact (SSC) on salivary cortisol, parental stress, parental depression, and breastfeeding. STUDY
designThis is a randomised study engaging families of late preterm infants (32-35 weeks gestation). Salivary cortisol reactivity was measured in infants during a nappy change at one month corrected age, and in infants and mothers during still-face at four month corrected age. Both parents completed the Swedish Parenthood Stress Questionnaire (SPSQ) at one month and the Edinburgh Postnatal Depression Scale (EPDS) at one and four months. Ainsworth's sensitivity scale was used to control for parental sensitivity. SUBJECTS: Thirty-seven families from two different neonatal care units in Sweden, randomised to either almost continuous SSC or standard care (SC).
resultsInfants randomised to SSC had a lower salivary cortisol reactivity at one month (p=0.01). There was a correlation between the mothers' and the preterm infants' salivary cortisol levels at four months in the SSC group (ρ=0.65, p=0.005), but not in the SC group (ρ=0.14, p=0.63). Fathers in SSC scored lower on the SPSQ sub-scale spouse relationship problems compared to fathers in SC (p<0.05).
conclusionsAlmost continuous SSC decreases infants' cortisol reactivity in response to handling, improves the concordance between mothers' and infants' salivary cortisol levels, and decreases fathers' experiences of spouse relationship problems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.