Evidence map›Paper›PMID 25545341›Full record

ArticleJournal of biomedical optics2014

Intravascular optical coherence tomography light scattering artifacts: merry-go-rounding, blooming, and ghost struts.

J Jacob Mancuso, David L Halaney, Sahar Elahi, Derek Ho, Tianyi Wang, Yongjian Ouyang, Jouke Dijkstra, Thomas E Milner, Marc D Feldman

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

J Jacob MancusoThe University of Texas Health Science Center at San Antonio, Division of Cardiology, Department of Medicine, 7703 Floyd Curl Drive, San Antonio, Texas 78229, United StatesbSouth Texas Veterans Health Care System, The Department of Veterans Affairs, San A.
David L HalaneyThe University of Texas Health Science Center at San Antonio, Division of Cardiology, Department of Medicine, 7703 Floyd Curl Drive, San Antonio, Texas 78229, United StatesbSouth Texas Veterans Health Care System, The Department of Veterans Affairs, San A.
Sahar ElahiThe University of Texas at Austin, Department of Biomedical Engineering, 1 University Station C0800, Austin, Texas 78712, United States.
Derek HoThe University of Texas at Austin, Department of Biomedical Engineering, 1 University Station C0800, Austin, Texas 78712, United States.
Tianyi WangThe University of Texas at Austin, Department of Biomedical Engineering, 1 University Station C0800, Austin, Texas 78712, United States.
Yongjian OuyangThe University of Texas Health Science Center at San Antonio, Division of Cardiology, Department of Medicine, 7703 Floyd Curl Drive, San Antonio, Texas 78229, United States.
Jouke DijkstraLeiden University Medical Center, Division of Image Processing, Department of Radiology, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
Thomas E MilnerThe University of Texas at Austin, Department of Biomedical Engineering, 1 University Station C0800, Austin, Texas 78712, United States.
Marc D FeldmanThe University of Texas Health Science Center at San Antonio, Division of Cardiology, Department of Medicine, 7703 Floyd Curl Drive, San Antonio, Texas 78229, United StatesbSouth Texas Veterans Health Care System, The Department of Veterans Affairs, San A.

Funding

Training in Medical ImagingT32EB001040 · NIBIB · DUKE UNIVERSITY · PI NIGHTINGALE, KATHRYN RADABAUGH · 2003 to 2018
$4.4M
NIBIB NIH HHS T32 EB001040
6 · The paper itself

Abstract

We sought to elucidate the mechanisms underlying two common intravascular optical coherence tomography (IV-OCT) artifacts that occur when imaging metallic stents: “merry-go-rounding” (MGR), which is an increase in strut arc length (SAL), and “blooming,” which is an increase in the strut reflection thickness (blooming thickness). Due to uncontrollable variables that occur in vivo, we performed an in vitro assessment of MGR and blooming in stented vessel phantoms. Using Xience V and Driver stents, we examined the effects of catheter offset, intimal strut coverage, and residual blood on SAL and blooming thickness in IV-OCT images. Catheter offset and strut coverage both caused minor MGR, while the greatest MGR effect resulted from light scattering by residual blood in the vessel lumen, with 1% hematocrit (Hct) causing a more than fourfold increase in SAL compared with saline (p<0.001 ). Residual blood also resulted in blooming, with blooming thickness more than doubling when imaged in 0.5% Hct compared with saline (p<0.001 ). We demonstrate that a previously undescribed mechanism, light scattering by residual blood in the imaging field, is the predominant cause of MGR. Light scattering also results in blooming, and a newly described artifact, three-dimensional-MGR, which results in “ghost struts” in B-scans.

Indexed as

ArtifactsAnimalsBlood Physiological PhenomenaEndovascular ProceduresImage Processing, Computer-AssistedLasersLightModels, CardiovascularPhantoms, ImagingReproducibility of ResultsScattering, RadiationStentsSwineTomography, Optical Coherence

Identifiers

PMID25545341
PMCPMC4659478

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.