Evidence map›Paper›PMID 25545101›Full record

ReviewNutrients2014

The impact of diet and lifestyle on gut microbiota and human health.

Michael A Conlon, Anthony R Bird

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrients, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04510324 (Plant-Based Meat vs Animal "Red" Meat), which is not on this map. Cited by 744 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
744citing papers in PubMed, 8 pooled it
24.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04510324 nacompletednot on this mapstarted 2020, after this paper: background citation

Plant-Based Meat vs Animal "Red" Meat: a Randomized Cross-over Trial

TypeinterventionalSponsorMcGill University Health Centre/Research Institute of the McGill University Health CentreRan2020 to 2023Enrolled41ConditionsInflammatory ResponseArmsRed meat patties group, Plant-based patties group
3 · Its place in the literature

Who cites it

744 citing papers in PubMed, 8 syntheses or guidelines pooled it, 1,516 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  5. Mucosal immune response in biology, disease prevention and treatment.Signal transduction and targeted therapy · 2025
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Trial
  10. Frontiers in nutrition · 2026
    Trial
  11. Trial
  12. Trial
  13. Nurturing gut health: A comprehensive framework.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article

684 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael A ConlonCSIRO Food and Nutrition Flagship, Kintore Ave, Adelaide, SA 5000, Australia. michael.conlon@csiro.au.
Anthony R BirdCSIRO Food and Nutrition Flagship, Kintore Ave, Adelaide, SA 5000, Australia. tony.bird@csiro.au.
Animal, Food and Health Sciences · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is growing recognition of the role of diet and other environmental factors in modulating the composition and metabolic activity of the human gut microbiota, which in turn can impact health. This narrative review explores the relevant contemporary scientific literature to provide a general perspective of this broad area. Molecular technologies have greatly advanced our understanding of the complexity and diversity of the gut microbial communities within and between individuals. Diet, particularly macronutrients, has a major role in shaping the composition and activity of these complex populations. Despite the body of knowledge that exists on the effects of carbohydrates there are still many unanswered questions. The impacts of dietary fats and protein on the gut microbiota are less well defined. Both short- and long-term dietary change can influence the microbial profiles, and infant nutrition may have life-long consequences through microbial modulation of the immune system. The impact of environmental factors, including aspects of lifestyle, on the microbiota is particularly poorly understood but some of these factors are described. We also discuss the use and potential benefits of prebiotics and probiotics to modify microbial populations. A description of some areas that should be addressed in future research is also presented.

Indexed as

Energy IntakeFeeding BehaviorLife StyleMicrobiotaDietary CarbohydratesDietary FatsDietary ProteinsDiet, WesternGastrointestinal TractHumansObservational Studies as TopicPolyphenolsPrebioticsProbioticsDietary CarbohydratesDietary FatsDietary ProteinsPolyphenolsPrebiotics

Identifiers

PMID25545101
PMCPMC4303825
OpenAlexW2124557952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.