ArticleContemporary clinical trials2015
Using registries to recruit subjects for clinical trials.
Article in Contemporary clinical trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The usage of population and disease registries as pre-screening tools for clinical trials, a systematic review.Systematic reviews · 2024Pooled it
- Impact of a psychoeducational intervention to improve caregiver knowledge and attitudes toward palliative cancer care.Patient education and counseling · 2025Trial
- Opportunities to Increase Science of Diversity and Inclusion in Clinical Trials: Equity and a Lack of a Control.Journal of the American Heart Association · 2023Review
- Minimum data set for treatment effectiveness in pyoderma gangrenosum (MIDSTEP): an international protocol of an e-Delphi study to develop a clinical physician-driven treatment effectiveness registry on behalf of the UPGRADE initiative.Archives of dermatological research · 2023Article
- Double-counting of populations in evidence synthesis in public health: a call for awareness and future methodological development.BMC public health · 2022Article
- Feasibility of supported self-management with a pictorial action plan to improve asthma control.NPJ primary care respiratory medicine · 2022Article
- Recruitment of Patients With Amyotrophic Lateral Sclerosis for Clinical Trials and Epidemiological Studies: Descriptive Study of the National ALS Registry's Research Notification Mechanism.Journal of medical Internet research · 2021Article
- Analysis of the reasons for screening failure in phase I clinical trials in China: a retrospective study of the clinical trials screening process.Annals of translational medicine · 2021Article
- Heregulin (HRG) assessment for clinical trial eligibility testing in a molecular registry (PRAEGNANT) in Germany.BMC cancer · 2020Article
- Increasing Ancestral Diversity in Lupus Trials: Ways Forward.Rheumatic diseases clinics of North America · 2020Review
- Genetic Testing and Surveillance of Young Breast Cancer Survivors and Blood Relatives: A Cluster Randomized Trial.Cancers · 2020Article
- Registry-based trials: a potential model for cost savings?Cardiology in the young · 2020Article
- Audience segmentation as a strategy for enhancing the use of research registries for recruiting patients into clinical trials.Contemporary clinical trials communications · 2020Article
- Effective recruitment for practice-based research: Lessons from the REAL HEALTH-Diabetes Study.Contemporary clinical trials communications · 2019Article
- The "rights" of precision drug development for Alzheimer's disease.Alzheimer's research & therapy · 2019Review
- Improving the efficiency of trials using innovative pilot designs: the next phase in the conduct and reporting of pilot and feasibility studies.Pilot and feasibility studies · 2018Article
- Facilitating access to health research through a participatory research register: a feasibility study in outpatient clinics.Pilot and feasibility studies · 2018Article
- Evaluating the Efficacy of a Registry linked to a Consent to Re-Contact Program and Communication Strategies for Recruiting and Enrolling Participants into Clinical Trials.Contemporary clinical trials communications · 2017Article
- A cross-cutting approach to enhancing clinical trial site success: The Department of Veterans Affairs' Network of Dedicated Enrollment Sites (NODES) model.Contemporary clinical trials communications · 2017Article
- Characterization and utilization of an international neurofibromatosis web-based, patient-entered registry: An observational study.PloS one · 2017Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
aimWe studied the use of patient/disease registries to recruit potential subjects for prospective clinical trials - describing the number, types and major benefits of using this approach.
methodsIn December 2013, we conducted a focused database search in PubMed, EMBASE, and Web of Science for studies (English language only) that used registries to recruit subjects for clinical trials published in 2004-2013. Of the 233 unique citations identified, 21 used registries to recruit subjects - 10 papers and 11 abstracts. Pearling and search for subsequent full papers of the abstracts identified 4 more papers.
resultsOur analysis, based on these 25 citations, showed that 14 are related to cancer, 3 to diabetes mellitus, 1 each to stroke, asthma, and celiac disease and 5 are disease neutral. Many types of registries (population-based cancer, quality improvement, disease-specific, web-based disease-neutral registries, local general practice registers, and national health database) are used to recruit subjects for clinical trials and uncover new knowledge. Overall, 16 registries are in the US, 4 in UK, 1 each in Canada, Spain, and Australia and 1 involved in many countries. Registries can identify very large number of subjects for screening for eligibility for clinical trials, especially in very large trials, rare disease trials, and trials involving minority patients.
conclusionsRegistries can retrospectively identify very large numbers of potential subjects for screening for eligibility and enrollment in prospective clinical trials. This matching can lead to more timely recruitment and help solve a major problem in conducting clinical trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.